Results 11 to 20 of about 250,265 (247)
Ferrochelatase regulates retinal neovascularization [PDF]
The FASEB Journal, 2020 Abstract Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo. But FECH has not been explored in retinal neovascularization, which underlies diseases like proliferative diabetic ...
Sardar Pasha Sheik Pran Babu +2 more
openaire +4 more sources
Scientific Reports, 2023 Retinal pathological neovascularization involves endothelial cells, pericytes, photoreceptor cells, ganglion cells, and glial cells, whose roles remain unclear.
Lushu Chen +5 more
doaj +2 more sources
Indian Journal of Ophthalmology, 2018 We report concurrent management of rhegmatogenous retinal detachment and myopic choroidal neovascularization in the left eye of a 24-year-old female who presented with sudden dimness of vision due to retinal detachment and choroidal neovascularization ...
Kumar Saurabh +3 more
doaj +2 more sources
Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization. [PDF]
PLoS ONE, 2013 The development and maintenance of retinal vasculature require a precise balance between pro-angiogenic and anti-angiogenic factors. However, mechanisms underlying normal homeostasis of retinal vasculature and pathological changes of disrupted retinal ...
Chun-hong Xia +3 more
doaj +2 more sources
IL-17A Enhances Retinal Neovascularization
International Journal of Molecular Sciences, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of vision loss.
Brooklyn E. Taylor +7 more
openaire +3 more sources
Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy
Case Reports in Ophthalmology, 2017 We report a case of peripheral retinal neovascularization and vitreous hemorrhage in the setting of HIV retinopathy that can serve to extend the clinical spectrum of this condition.
Kim Jiramongkolchai +2 more
doaj +2 more sources
Microglial TSPAN4-Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune-Vascular Crosstalk. [PDF]
Adv Sci (Weinh)Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Xu J +12 more
europepmc +2 more sources
FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice
Cell Reports, 2017 Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu +12 more
doaj +2 more sources
Peripheral retinal neovascularization in a patient with obstructive sleep apnea
American Journal of Ophthalmology Case Reports, 2022 Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani +4 more
doaj +1 more source
The progress of prophylactic treatment in retinopathy of prematurity [PDF]
International Journal of Ophthalmology, 2018 Retinopathy of prematurity (ROP) is a retinal vascular disorder frequently found in premature infants. Different therapeutic strategies have been developed to treat ROP.
Hong-Bing Zhang +3 more
doaj +1 more source