IL-17A Enhances Retinal Neovascularization
International Journal of Molecular Sciences, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of ...
Brooklyn E. Taylor +7 more
semanticscholar +2 more sources
Ferrochelatase regulates retinal neovascularization
bioRxiv, 2020 Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo.
Sardar Pasha Sheik Pran Babu +2 more
semanticscholar +2 more sources
Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization. [PDF]
PLoS ONE, 2013 The development and maintenance of retinal vasculature require a precise balance between pro-angiogenic and anti-angiogenic factors. However, mechanisms underlying normal homeostasis of retinal vasculature and pathological changes of disrupted retinal ...
Chun-hong Xia +3 more
doaj +2 more sources
Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report
Case Reports in Ophthalmology, 2023 We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri +4 more
doaj +2 more sources
Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy
Case Reports in Ophthalmology, 2017 We report a case of peripheral retinal neovascularization and vitreous hemorrhage in the setting of HIV retinopathy that can serve to extend the clinical spectrum of this condition.
Kim Jiramongkolchai +2 more
doaj +2 more sources
Methyltransferase-like 14 suppresses the retinal neovascularization by reducing HIF-1α in proliferative retinopathy [PDF]
European Journal of Medical ResearchBackground Proliferative retinopathy (PR), a leading cause of visual impairment, is characterized by pathological retinal neovascularization.
Jitian Guan +7 more
doaj +2 more sources
A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity [PDF]
Scientific ReportsExtraretinal neovascularization is a hallmark of treatment-requiring retinopathy of prematurity (ROP). Optical coherence tomography angiography (OCTA) offers vascular flow and depth information not available from indirect ophthalmoscopy and structural ...
Xi Chen +10 more
doaj +2 more sources
PLoS ONE, 2017 Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-induced retinopathy (OIR) in young mice is widely used as a model to investigate the underlying pathological mechanisms and develop therapeutic interventions.
Pilar Villacampa +8 more
doaj +2 more sources
CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish [PDF]
Frontiers in PharmacologyRetinal neovascularization is a common feature of several ocular neovascular diseases, which are the leading cause of blindness in the world. Current treatments are administered through invasive intravitreal injections, leading to poor patient compliance,
Jun-long Zhang +4 more
doaj +2 more sources
FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice
Cell Reports, 2017 Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu +12 more
doaj +2 more sources