Results 21 to 30 of about 41,612 (247)

A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity [PDF]

Scientific Reports
Extraretinal neovascularization is a hallmark of treatment-requiring retinopathy of prematurity (ROP). Optical coherence tomography angiography (OCTA) offers vascular flow and depth information not available from indirect ophthalmoscopy and structural ...
Xi Chen, Ryan Imperio, Christian Viehland, Pujan R. Patel, Du Tran-Viet, Shwetha Mangalesh, S. Grace Prakalapakorn, Sharon F. Freedman, Joseph A. Izatt, Cynthia A. Toth, BabySTEPS Group   +10 more
doaj   +2 more sources

Retinal ischemia with neovascularization in cisplatin related retinal toxicity

American Journal of Ophthalmology, 2006
PURPOSE: To report a case of macular ischemia and retinal neovascularization in a patient who received cisplatin related ...
Sahu, Anjana, Kwan, Anthony S.L., Palexes, George   +2 more
core   +6 more sources

VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]

, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Ogura, Y, Ng, Yin-Shan, Adamis, Anthony P., Kenji Yamashiro, Usui, Tomohiko, Hida, Tetsuo, Yuichi Kaji, Evangelos S. Gragoudas, Yin-Shan Ng, Shiro Amano, Amano, Shiro, Miller, Joan W., Yuichiro Ogura, Patricia A. D'Amore, Ambati, Jayakrishna, Shima, David T., Gragoudas, Evangelos S., Miller, JW, D'Amore, PA, Yoshihisa Oguchi, Hida, T, Ishida, S, Gragoudas, ES, Usui, T, Tetsuo Hida, Ogura, Yuichiro, Tomohiko Usui, Jayakrishna Ambati, Shima, DT, Joan W. Miller, Kaji, Yuichi, D\u27Amore, Patricia A., Ambati, J, Adamis, AP, Anthony P. Adamis, Kaji, Y, Yamashiro, K, Amano, S, Oguchi, Y, Oguchi, Yoshihisa, David T. Shima, Yamashiro, Kenji, Susumu Ishida, Ishida, Susumu, Ng, YS   +44 more
core   +1 more source

Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. [PDF]

PLoS ONE, 2017
Vitamin D provides a significant benefit to human health, and its deficiency has been linked to a variety of diseases including cancer. Vitamin D exhibits anticancer effects perhaps through inhibition of angiogenesis. We previously showed that the active
Nasim Jamali, Shoujian Wang, Soesiawati R Darjatmoko, Christine M Sorenson, Nader Sheibani   +4 more
doaj   +1 more source

Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. [PDF]

, 2018
Purpose Neovascularization is a major cause of blindness in various ocular diseases. Bioactive sphingosine 1-phosphate (S1P), synthesized by two sphingosine kinases (Sphk1, Sphk2), emerged as a key player in a multitude of cellular processes ...
Koch, Alexander, Devraj, Kavi, Lars-Olof Hattenbach, Vutukuri, Rajkumar, Yannick Schreiber, Huwiler, Andrea, Katrin Schröder, Kavi Devraj, Popp, Rüdiger, Alexander Koch, Martin Stumpf, Pfeilschifter, Josef, Nerea Ferreirós, Andrea Huwiler, Jeanette Eresch, Eresch, Jeanette, Hattenbach, Lars-Olof, Waltraud Pfeilschifter, Rüdiger Popp, Stumpf, Martin, Rajkumar Vutukuri, Ferreirós, Nerea, Pfeilschifter, Waltraud, Josef Pfeilschifter, Schreiber, Yannick, Schröder, Katrin   +25 more
core   +1 more source

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

Frontiers in Pharmacology, 2020
Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan, Xin-Xin Li, De-Wei Peng, Wen-Meng Zhang, Jia Qu, Fan Lu, Fan Lu, Robert J. D’Amato, Robert J. D’Amato, Zai-Long Chi, Zai-Long Chi   +10 more
doaj   +1 more source

Targeting Neuroinflammation in Neovascular Retinal Diseases

Frontiers in Pharmacology, 2020
Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells.
Tianxi Wang, Demetrios I. Tsirukis, Ye Sun   +2 more
doaj   +1 more source

Concurrent management of myopic choroidal neovascularization and rhegmatogenous retinal detachment with intravitreal antivascular endothelial growth factor during primary retinal detachment repair

Indian Journal of Ophthalmology, 2018
We report concurrent management of rhegmatogenous retinal detachment and myopic choroidal neovascularization in the left eye of a 24-year-old female who presented with sudden dimness of vision due to retinal detachment and choroidal neovascularization ...
Kumar Saurabh, Rupak Roy, Nicey Roy Thomas, Maitreyi Chowdhury   +3 more
doaj   +1 more source

Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature. [PDF]

PLoS ONE, 2017
Apoptosis plays a central role in developmental and pathological angiogenesis and vessel regression. Bim is a pro-apoptotic Bcl-2 family member that plays a prominent role in both developmental and pathological ocular vessel regression, and ...
Shoujian Wang, Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Zafer Gurel, Catherine M Wintheiser, Andreas Strasser, Volkhard Lindner, Nader Sheibani, Christine M Sorenson   +9 more
doaj   +1 more source

Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization

Neural Regeneration Research, 2023
Inhibiting retinal neovascularization is the optimal strategy for the treatment of retina-related diseases, but there is currently no effective treatment for retinal neovascularization.
Yong Yu, Li-Kun Xia, Yu Di, Qing-Zhu Nie, Xiao-Long Chen   +4 more
doaj   +1 more source