Results 81 to 90 of about 1,691,306 (277)

Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia.

Investigative Ophthalmology and Visual Science, 2019
Purpose The purpose of this study was to study changes in choroidal thickness (ChT) and choroidal blood perfusion (ChBP), and the correlation between them, in guinea pig myopia. Methods The reliability of optical coherence tomography angiography (OCTA)
Sen Zhang, Guoyun Zhang, Xuan Zhou, Renchang Xu, Siyao Wang, Zhenqi Guan, Juan Lu, Nethrajeith Srinivasalu, M. Shen, Zi Jin, J. Qu, Xiangtian Zhou   +11 more
semanticscholar   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging [PDF]

International Journal of Ophthalmology, 2018
AIM: To evaluate choroidal thickness, medium choroidal vessel thickness (MCVT) and large choroidal vessel thickness (LCVT) in normal children and adult subjects.
Daren Hanumunthadu, Jorge Ruiz-Medrano, Sunila Dumpala, Ayesha Jabeen, Asiya Jabeen, Abhilash Goud, José M Ruiz-Moreno, Jay Chhablani   +7 more
doaj   +1 more source

Evaluation of the Choroidal Thickness Using High-Penetration Optical Coherence Tomography With Long Wavelength in Highly Myopic Normal-Tension Glaucoma [PDF]

, 2012
PURPOSE:To evaluate the choroidal thickness by high-penetration optical coherence tomography (OCT) using long wavelength in highly myopic normal-tension glaucoma (NTG).DESIGN:Cross-sectional retrospective study.METHODS:SETTINGS:Institutional.PARTICIPANTS:
IKUNO YASUSHI, MATSUSHITA KENJI, MIKI ATSUYA, NISHIDA KOHJI, USUI SHINICHI, YASUNO YOSHIAKI, 安野 嘉晃   +6 more
core   +1 more source

CHOROIDAL THICKNESS AND VASCULARITY VARY WITH DISEASE SEVERITY AND SUBRETINAL DRUSENOID DEPOSIT PRESENCE IN NONADVANCED AGE-RELATED MACULAR DEGENERATION.

Retina, 2020
PURPOSE To investigate how choroidal features vary with age-related macular degeneration (AMD) severity in early-intermediate disease. METHODS One hundred fifty-one eyes of 151 participants >50 years with no to intermediate AMD were analyzed with ...
T. Keenan, Brandon Klein, E. Agrón, E. Chew, C. Cukras, W. Wong   +5 more
semanticscholar   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Attenuation of choroidal tickness in patients with Alzheimer disease: evidence from an Italian prospective study [PDF]

, 2017
INTRODUCTION: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39 age ...
Campanelli, A, D'Antonio, Fabrizia, DE LENA, Carlo, Gharbiya, M., Imbriano, L, Mallone, Fabiana, Marcelli, Michela, Trebbastoni, A   +7 more
core   +1 more source

Topographic Variations of Choroidal Thickness in Healthy Eyes on Swept-Source Optical Coherence Tomography

Investigative Ophthalmology and Visual Science, 2020
Purpose To assess topographic variations of choroidal thickness (CT) in the fovea and beyond in healthy eyes. Methods This cross-sectional study included healthy subjects ≤ 55 years of age with axial lengths (22–26 mm) and refractive error margins (–4D, +
S. Touhami, E. Philippakis, S. Mrejen, A. Couturier, Céline Casteran, Priscille Levent, R. Tadayoni, A. Gaudric   +7 more
semanticscholar   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Deep learning algorithms to segment and quantify the choroidal thickness and vasculature in swept-source optical coherence tomography images

Journal of Innovative Optical Health Sciences, 2020
Accurate segmentation of choroidal thickness (CT) and vasculature is important to better analyze and understand the choroid-related ocular diseases.
Gu Zheng, Yanfeng Jiang, Ce Shi, Hanpei Miao, Xiangle Yu, Yiyi Wang, Sisi Chen, Zhiyang Lin, Weicheng Wang, F. Lu, M. Shen   +10 more
semanticscholar   +1 more source