Results 71 to 80 of about 4,325 (224)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Pre‐operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno‐arterial extracorporeal membrane oxygenation or cardiac surgery

Journal of Medical Radiation Sciences, EarlyView.
A pre‐cannulation survey of the circle of Willis (CoW) using transcranial Doppler (TCD) ultrasound was implemented to assess cerebral collateral circulation in children undergoing VA ECMO or cardiac surgery with cervical cannulation. The technique, in use since 2019, employs high‐end ultrasound platforms to assess brain morphology, haemorrhage and ...
Tristan Reddan, Michael Malouf, Prem Venugopal, Jennifer Powell   +3 more
wiley   +1 more source

Early choroidal structure and choroidal vascularity index change after carotid stenting

Photodiagnosis and Photodynamic Therapy, 2022
We aimed to evaluate changes in subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) in the first postoperative day and month in patients with severe internal carotid artery (ICA) stenosis after ICA stenting.The patients who diagnosed with severe ICA stenosis and was performed ICA stenting were included in the study. Patients with
Gonul Karatas, Durusoy, Gulsah, Gumus, Mehmet, Onay, Cetin Murat, Altay, Ali Burak, Binboga   +4 more
openaire   +2 more sources

CRPPA exon 6–9 deletion as a founder mutation in Chinese patients with dystroglycanopathy

Pediatric Investigation, EarlyView.
Analysis of sixteen Chinese dystroglycanopathy patients reveals a founder mutation (CRPPA exon 6–9 deletion) in 25% of cases and expands the phenotypic spectrum from severe muscle‐eye‐brain disease to limb‐girdle muscular dystrophy. ABSTRACT Importance Dystroglycanopathies (DGPs) are a group of muscular dystrophies with abnormal glycosylation of ...
Jihang Luo, Yidan Liu, Danyu Song, Shiqi Yang, Xiaona Fu, Lin Ge, Cuijie Wei, Liya Cui, Yanbin Fan, Huaxia Luo, Yanwei He, Jin Xu, Qiang Shen, Yuxuan Guo, Motoi Kanagawa, Tatsushi Toda, Jingmin Wang, Hong Zhang, Hui Xiong   +18 more
wiley   +1 more source

Linking cardiological parameters and choroidal changes in patients with precapillary pulmonary hypertension: a cross-sectional study

Scientific Reports
Diagnosing precapillary pulmonary hypertension (PPH) is challenging, and prognosis remains poor. This study aims to explore the pathogenesis of choroidal changes in these patients and assess whether choroidal parameters could serve as noninvasive ...
Agnieszka Zonenberg, Katarzyna Ptaszyńska, Anna Szwedowicz, Emilia Sawicka-Śmiarowska, Remigiusz Kazimierczyk, Barbara Pieklarz, Izabela Zawadzka, Iwona Obuchowska, Aleksandra Leoniuk, Joanna Konopińska, Karol Kamiński, Diana A. Dmuchowska   +11 more
doaj   +1 more source

Retinal and choroidal changes in steroid-associated central serous chorioretinopathy

International Journal of Retina and Vitreous, 2018
Background To evaluate the retinal and choroidal alterations in steroid-associated central serous chorioretinopathy (CSC) in comparison to idiopathic CSC. Methods In this retrospective cohort study, swept source optical coherence tomography scans of eyes
Vikas Ambiya, Abhilash Goud, Mohammed Abdul Rasheed, Sankeert Gangakhedkar, Kiran Kumar Vupparaboina, Jay Chhablani   +5 more
doaj   +1 more source

Nodular Posterior Scleritis: Clinico-Sonographic Characteristics and Proposed Diagnostic Criteria [PDF]

, 2015
Purpose: To report the clinical and ultrasound features and outcomes of a series of nodular posterior scleritis. / Methods: Retrospective medical record review of 11 consecutive patients with nodular posterior scleritis.
Agrawal, R, Lavric, A, Pavesio, C, Restori, M, Sagoo, MS   +4 more
core  

Choroidal Vascular Hyperpermeability and Punctate Hyperfluorescent Spot in Choroidal Neovascularization

Investigative Opthalmology & Visual Science, 2015
To evaluate the prevalence of choroidal vascular hyperpermeability and punctate hyperfluorescent spots in eyes with choroidal neovascularization (CNV).This retrospective, observational study included 382 eyes with typical exudative AMD (97 eyes), polypoidal choroidal vasculopathy (PCV, 163 eyes), retinal angiomatous proliferation (RAP, 37 eyes), or ...
Jae Hui, Kim, Young Suk, Chang, Tae Gon, Lee, Chul Gu, Kim   +3 more
openaire   +2 more sources

Retinal imaging in pre‐eclamptic pregnancy: systematic review

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To explore potential changes in retinal structures in pregnant women with pre‐eclampsia (PE). Methods This was a systematic review of the literature on retinal assessment in pregnancies complicated by PE. PubMed, EMBASE via Ovid, The Cochrane Library and Scopus databases were searched in July 2025 using an a‐priori‐designed protocol ...
D. Kitmiridou, I. Mitrogiannis, M. Charakida, K. H. Nicolaides   +3 more
wiley   +1 more source