Results 131 to 140 of about 166,399 (264)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Strong Fully Reprocessable Engineered Wood Composites

Advanced Materials, EarlyView.
Engineering a hyperbranched adhesive with complementary imine‐bond and hydrogen‐bond networks, combining it with wood particles to fabricate the wood composite (WP/HTP) under mild hot‐pressing conditions. The WP/HTP exhibits 100% mechanical strength recovery after three cycles of reprocessing, and the reprocessed modulus of rupture (MOR) and modulus of
Xilin Zhang, Zheng Liu, Zhezhe Zhou, Mark Lynch, Jianzhang Li, Paulomi Burey, Jingchao Li, Cheng Zhang, Qiang Gao, Pingan Song   +9 more
wiley   +1 more source

Chow groups with twisted coefficients

Rost defined the Chow group of algebraic cycles with coefficients in a locally constant torsion etale sheaf. We generalize the definition to allow non-torsion coefficients. Chow groups with twisted coefficients are related to Serre's notion of "negligible cohomology" for finite groups.
openaire   +2 more sources

Reducing Interfacial Separation Force in High‐Speed Constrained‐Surface Projection Stereolithography Using a Dual‐Modulus Silicone Release Film

Advanced Materials Interfaces, EarlyView.
A dual‐modulus silicone release film creates distributed stress concentrations at high‐/low‐modulus boundaries, triggering multi‐site crack initiation and rapid interfacial detachment. The architecture lowers the peak separation force by 97.6%, shortens detachment time, and enables stable continuous projection stereolithography at 720 mm h−1, offering ...
Xiaogang Li, Xiaoqing Kang, Hong Xiao, Yugang Duan   +3 more
wiley   +1 more source

Fixed-dose streptozotocin combined with high-fat diet induces a stable type 2 diabetes-like phenotype in C57BL/6J mice. [PDF]

Dis Model Mech
Fryklund C, Simonsson C, Hellberg A, Malmberg J, Stenkula KG, Swanberg M.   +5 more
europepmc   +1 more source

Multilayer Biobased Poly(ethylene furanoate)/Graphene Oxide Nanofibrous Membranes With Directional Water Transport for Efficient Microplastics Filtration

Advanced Materials Technologies, EarlyView.
A self‐assembled multilayer biobased PEF/GO nanofibrous membrane was developed by electrospinning for efficient PLA microplastics (MPs) filtration. The membrane combines superhydrophilicity, directional water transport, mechanical robustness, and a synergistic size‐exclusion interception and electrostatic repulsion MPs separation mechanism, enabling ...
Juraij Kandiyil, Sumayya Ansari, Prasanna Kumar S Mural, Yaser E. Greish, Adnan Younis, Akmal Nazir, Muhammad Z. Iqbal   +6 more
wiley   +1 more source

Maternal obesity in rats results in male-specific increases in genome-wide DNA methylation in postnatal offspring liver. [PDF]

Biol Open
Youngson NA, Corley SM, Hasebe K, Tajaddini A, Kendig MD, Morris MJ.   +5 more
europepmc   +1 more source

Liquid Metal Resistive Sensing Architectures for Measuring Diaphragm Strain Responses on Obstructed Surfaces

Advanced Materials Technologies, EarlyView.
A liquid metal‐based strain‐sensing architecture to measure the deformation of a circular diaphragm against obstructed surfaces is formulated using finite element modeling and confocal imaging to establish the mechanical framework and is utilized to control diaphragm‐induced confinement on a bead array, as validated by biomolecular loading level ...
Abdullah‐Bin Siddique, Jui‐Hong Weng, Deng‐Kai Yang, Chia‐Fu Chou, Nathan S. Swami   +4 more
wiley   +1 more source

Exceptional Elasto‐Dielectric Properties in a Highly Flexible Dielectric Elastomer Composite: The Key Roles of Parallel Elastic Nanofibers

Advanced Materials Technologies, EarlyView.
Soft dielectric elastomer composites often face a trade‐off between enhanced dielectric properties and mechanical compliance. Here, a parallel‐aligned polyurethane nanofiber network embedded in PDMS creates a flexible, durable composite with increased permittivity, low modulus, and fatigue stability after 100,000 cycles.
Yi Ge, Jiacheng Zhou, Yuxin Tan, Juntao Zhao, Junhui Huang, Lei Fu, Zepeng Lv, Jun Zhou, Yusuke Yamauchi, Kai Wu   +9 more
wiley   +1 more source

Pregnane X receptor deletion induces a lean phenotype in chow-fed mice through a liver-ileum-muscle axis involving 6α-hydroxylated bile acids and Fgf15. [PDF]

Mol Metab
Benoit B, Jalabert A, Meugnier E, Chanon S, Vieille-Marchiset A, Beau A, Pesenti S, Loizon E, Vitalis O, Bendridi N, Nawrot M, Makki K, Le Magueresse-Battistoni B, Rieusset J, Michalski MC, Rainteau D, Chikh K, Vidal H, Ruzzin J.   +18 more
europepmc   +1 more source