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Alternate-day fat diet and exenatide modulate the brain leptin JAK2/STAT3/SOCS3 pathway in a fat diet-induced obesity and insulin resistance mouse model

open access: yesArchives of Medical Science, 2023
Introduction Obesity is one of the most burdensome health problems and is closely linked to leptin resistance. The study examined whether an alternate-day high-fat diet (ADF) and/or GLP-1 agonist (exenatide) modulate brain leptin resistance caused by a ...
Mona K. Tawfik   +4 more
doaj   +1 more source

Effect of Tocotrienols Derived from Annatto on Lipid Profile and Some Adipokine Hormones in Rats Fed a High-Fat Diet [PDF]

open access: yesBasrah Journal of Veterinary Research, 2023
Obesity is a metabolic condition that causes people to develop a variety of diseases and has emerged as a serious global public-health problem. Tocotrienol, a member of the vitamin E family that comes from the annatto bean (Bixa orellana), is special in ...
Eman Rahi, Nameer Khudhair
doaj   +1 more source

The Effect of Exercise on Serum Resistin and Leptin Values in Rats Fed with a High Fat Diet

open access: yesJournal of Contemporary Medicine, 2023
Aim: This study was performed to investigate the effect of exercise on serum resistin and leptin values in rats fed with a high-fat diet. Material and Method: 24 Wistar albino male rats were used in the study.
Nizamettin Günbatar, Bahattin Bulduk
doaj   +1 more source

Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. [PDF]

open access: yesPLoS ONE, 2013
Nonalcoholic steatohepatitis (NASH) is associated with caspase activation. However, a role for pro-inflammatory caspases or inflammasomes has not been explored in diet-induced liver injury.
Laura J Dixon   +4 more
doaj   +1 more source

Body fat accumulation in zebrafish is induced by a diet rich in fat and reduced by supplementation with green tea extract. [PDF]

open access: yesPLoS ONE, 2015
Fat-rich diets not only induce obesity in humans but also make animals obese. Therefore, animals that accumulate body fat in response to a high-fat diet (especially rodents) are commonly used in obesity research.
Shinichi Meguro   +2 more
doaj   +1 more source

High-intensity interval training ameliorates high-fat diet-induced elevation of aminotransferases in male Wistar rats [PDF]

open access: yesJournal of Shahrekord University of Medical Sciences, 2021
Background and aims: A high-fat diet increases triglyceride (TG) accumulations in hepatocytes and results in non-alcoholic fatty liver diseases (NAFLDs). In this regard, this study investigated the effect of high-intensity interval training (HIIT), along
Qazaleh Asqari   +3 more
doaj   +1 more source

Behavioral Feeding Circuit: Dietary Fat-Induced Effects of Inflammatory Mediators in the Hypothalamus

open access: yesFrontiers in Endocrinology, 2020
Excessive dietary fat intake has extensive impacts on several physiological systems and can lead to metabolic and nonmetabolic disease. In animal models of ingestion, exposure to a high fat diet during pregnancy predisposes offspring to increase intake ...
Kinning Poon
doaj   +1 more source

Risk of alternative diet therapy for elderly patients

open access: yesMedycyna Ogólna i Nauki o Zdrowiu, 2022
Introduction and objective The course of the aging process, among other things, depends on the lifestyle. Considering the influence of nutrition on the functioning of the body, it seems important to analyze the effects of using restrictive dietary models
Maja Miętkiewska, Paweł Bogdański
doaj   +1 more source

Rats Fed Diets with Different Energy Contribution from Fat Do Not Differ in Adiposity

open access: yesObesity Facts, 2014
Objective: To determine whether rats reaching the same body mass, having been fed either a low-fat (LFD) or a high-fat diet (HFD), differ in white adipose tissue (WAT) deposition.
Alexander D. Miras   +7 more
doaj   +1 more source

Impact of high-fat diet and hypoxia on the serum levels of main vasoconstrictors in male rabbits [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2017
Introduction: During atherosclerosis process, vasoconstriction phenomenon occurs which in turn leads to tissue hypoxia. A few studies have been performed on the combination of atherosclerosis and hypoxia as stressors that may accelerate secretion of ...
Ali Aliyev   +4 more
doaj   +1 more source

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