Results 31 to 40 of about 15,948,723 (305)

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function.

open access: yesPLoS ONE, 2012
BackgroundAn Alternating high- cholesterol dietary regimen has proven to be beneficial when compared to daily high- cholesterol feeding. In the current study we explored whether the same strategy is applicable to a high- fat dietary regimen.ObjectiveTo ...
Gopala K Yakala   +7 more
doaj   +1 more source

Maternal High-Fat Diet and Offspring Hypertension

open access: yesInternational Journal of Molecular Sciences, 2022
The incidence of hypertension has increased to epidemic levels in the past decades. Increasing evidence reveals that maternal dietary habits play a crucial role in the development of hypertension in adult offspring. In humans, increased fat consumption has been considered responsible for obesity and associated diseases. Maternal diets rich in saturated
You-Lin Tain, Chien-Ning Hsu
openaire   +2 more sources

Dose-dependent effects of dietary fat on development of obesity in relation to intestinal differential gene expression in C57BL/6J mice [PDF]

open access: yes, 2011
Excessive intake of dietary fat is known to be a contributing factor in the development of obesity. In this study, we determined the dose-dependent effects of dietary fat on the development of this metabolic condition with a focus on changes in gene ...
Boekschoten, Mark V.   +43 more
core   +2 more sources

Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

open access: yesPharmaceutical Sciences, 2016
Background: There are many methods for inducing non-alcoholic fatty liver disease (NAFLD) in experimental animals. Due to the diversity of these methods and different variables involved in choosing the appropriate one, this study aimed to examine the ...
Sara Shojaei Zarghani   +3 more
doaj   +1 more source

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice [PDF]

open access: yes, 2008
Background Obesity and insulin resistance are two major risk factors underlying the metabolic syndrome. The development of these metabolic disorders is frequently studied, but mainly in liver, skeletal muscle, and adipose tissue.
Mechteld M Grootte Bromhaar   +34 more
core   +2 more sources

Dietary-induced hypertrophic–hyperplastic obesity in mice

open access: yesJournal of Lipid Research, 1974
Metabolically intact NMRI mice and genetically obese NZO mice were fed ad lib. either a high-carbohydrate diet (standard) or a high-fat diet for a period of about 11 (NMRI mice) or 38 (NZO mice) wk.
L. Herberg   +3 more
doaj   +1 more source

Effect of the dietary fat quality on insulin sensitivity. [PDF]

open access: yes, 2008
Recent evidence shows that specific fatty acids affect cell metabolism, modifying the balance between fatty acid oxidation and lipogenesis. These effects may have important implications in addressing the present epidemic of nutrition-related chronic ...
Aguirre, Carolina A   +7 more
core   +1 more source

High fat diet induced diabetic cardiomyopathy [PDF]

open access: yesProstaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2011
In response to a chronic high plasma concentration of long-chain fatty acids (FAs), the heart is forced to increase the uptake of FA at the cost of glucose. This switch in metabolic substrate uptake is accompanied by an increased presence of the FA transporter CD36 at the cardiac plasma membrane and over time results in the development of cardiac ...
Dirkx, Ellen   +4 more
openaire   +2 more sources

Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice

open access: yes, 2012
Aims: to determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring.Methods: female C57BL6J mice were fed an obesogenic high fat diet (HF, 45%
Geraldine F Clough   +41 more
core   +1 more source

Effect of high fat, high fat and high fructose diet on hyperuricemia in rats

open access: yesShipin yu jixie
[Objective] This study aimed to investigate the effects of high fat diet and high fat and high fructose diet on uric acid level and liver and kidney function in hyperuricemia (HUA) rats.
CHE Yingjuan   +4 more
doaj   +1 more source

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