Results 21 to 30 of about 15,948,723 (305)

A high fat diet fosters elevated bisretinoids

open access: yesJournal of Biological Chemistry, 2023
High dietary fat intake is associated with metabolic dysregulation, but little is known regarding the effects of a high fat diet (HFD) on photoreceptor cell functioning. We explored the intersection of an HFD and the visual cycle adducts that form in photoreceptor cells by nonenzymatic reactions.
Kim, Hye Jin   +3 more
openaire   +2 more sources

High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts

open access: yesStem Cells International, 2022
Current research suggests that chronic high-fat dietary intake can lead to bone loss in adults; however, the mechanism by which high-fat diets affect the development of osteoporosis in individuals is unclear.
RunJiu Zhu   +8 more
doaj   +1 more source

Methylmercury-Induced Metabolic Alterations in Caenorhabditis elegans Are Diet-Dependent

open access: yesToxics, 2021
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. Chronic exposure to MeHg in human populations shows an association with diabetes mellitus and metabolic syndrome (MS).
Nicole Crawford   +9 more
doaj   +1 more source

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota [PDF]

open access: yes, 2011
Objective The gut microbiota, which is considered a causal factor in metabolic diseases as shown best in animals, is under the dual influence of the host genome and nutritional environment. This study investigated whether the gut microbiota per se, aside
Klopp, Christophe   +45 more
core   +1 more source

Orlistat exerts anti-obesity and anti-tumorigenic effects in a transgenic mouse model of endometrial cancer

open access: yesFrontiers in Oncology, 2023
IntroductionAmong all cancers, endometrial cancer is most strongly associated with obesity, with more than 65% of endometrial cancers attributable to obesity and being overweight.
Guangxu Xu   +17 more
doaj   +1 more source

Long-term weight maintenance and cardiovascular risk factors are not different following weight loss on carbohydrate-restricted diets high in either monounsaturated fat or protein in obese hyperinsulinaemic men and women [PDF]

open access: yes, 2007
The aim of this study was to determine after 52 weeks whether advice to follow a lower carbohydrate diet, either high in monounsaturated fat or low fat, high in protein had differential effects in a free-living community setting. Following weight loss on
Luscombe-Marsh, N.   +4 more
core   +1 more source

Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation [PDF]

open access: yes, 2014
Scope Investigate the influence of low-folate supply during pregnancy and lactation on obesity and markers of the metabolic syndrome in offspring, and how provision of a high-fat diet post weaning may exacerbate the resultant phenotype.
Sabine A. S. Langie   +16 more
core   +1 more source

Effects of Excess Energy Intake on Glucose and Lipid Metabolism in C57BL/6 Mice. [PDF]

open access: yesPLoS ONE, 2016
Excess energy intake correlates with the development of metabolic disorders. However, different energy-dense foods have different effects on metabolism.
Jing Pang   +5 more
doaj   +1 more source

Effects of a high‐fat diet on rat epididymis

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, 2023
AbstractThe epididymis plays an essential role in reproduction, promoting sperm cell maturation. In this study, we investigated the effects of a high‐fat diet (HFD) in the three regions of the epididymis of rats, including caput, corpus, and cauda. Our results showed an increase in malondialdehyde and a decrease in superoxide dismutase, which indicated
Sara Falvo   +6 more
openaire   +3 more sources

Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats [PDF]

open access: yes, 2013
Obesity, insulin resistance, hypertension and fatty liver, together termed metabolic syndrome, are key risk factors for cardiovascular disease. Chronic feeding of a diet high in saturated fats and simple sugars, such as fructose and glucose, induces ...
Alam, Md. Ashraful   +5 more
core   +1 more source

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