Results 141 to 150 of about 537,618 (293)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

open access: yesHepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres   +21 more
wiley   +1 more source

The Christian Ethics of Dante's Purgatory [PDF]

open access: yes, 2014
It might appear straightforward, on a first reading, that Dante’s Purgatory represents a penitential journey guided by Christian ethics to God. For most of the poem’s history, indeed, Purgatory has been read broadly in this way. In the second half of the
Corbett, George
core   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota   +8 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Undergraduates’ Perceptions of Ideal Learning Environments

open access: yes, 2007
Four hundred and fifty three undergraduate students were surveyed at one CCCU institution regarding perceptions of what “exists” and what they “value” related to university pedagogy, learning activities, assessments, and learning relationships ...
Hetzel, June, Walters, Keith
core  

Co‐Producing the Transition to Eating Disorder Youth Intervention: Experience‐Based Co‐Design Workshops Supporting Young People in Transition

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are severe and complex psychiatric illnesses, with adolescence and young adulthood representing particularly vulnerable periods for onset, relapse and disruptions in treatment. The transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) is especially complex ...
Maria Livanou   +19 more
wiley   +1 more source

Social Comparison and Its Association With Disordered Eating Symptoms: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk   +5 more
wiley   +1 more source

Is St. Thomas Aquinas’s Moral Teaching Christian? The Answer of Servais Pinckaers, O.P. [PDF]

open access: yes, 2015
Servais Pinckaers, in his most important work, The Sources of Christian Ethics, asks the provocative question: is the Moral Theology of St. Thomas Aquinas Christian or, alternatively, does Aquinas rely so much on the ethics of Aristotle that his teaching
Morrissey, Paul
core   +1 more source

Efficacy of the Intervention Against the Stigmatization of Men With Eating Disorders in Primary Healthcare (iSMEsH): Results From a Randomized Waitlist‐Controlled Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) in men are underdiagnosed and undertreated, partly due to stigma hindering help‐seeking. This randomized waitlist‐controlled study tested the efficacy of the iSMEsH online anti‐stigma intervention targeting German general practitioners (GPs) and medical students.
Martin S. Lehe   +3 more
wiley   +1 more source

Contact Lens Knowledge and Practices Among Students in the College of Health Sciences, University of Ghana: A Cross‐Sectional Study

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Background Contact lenses (CLs) are increasingly used worldwide for refractive error correction because of their optical, cosmetic, and functional advantages over spectacles. However, although their safe and effective use depends on adequate knowledge and proper hygiene practices, there is limited evidence on contact lens‐related knowledge ...
Naa Naamuah Tagoe   +4 more
wiley   +1 more source

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