Results 81 to 90 of about 2,781,563 (238)

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

open access: yesAdvanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed   +15 more
wiley   +1 more source

Die noodsaak om lyding, pyn, dood en boosheid tot betekenis te bring

open access: yesVerbum et Ecclesia, 2016
To make sense of suffering was always part and parcel of being human. Although the inadequacy of theodicies to provide meaningful theoretical frameworks resulted in a focus on practical responses, in this article a case has been made for the necessity to
Niekie Lamprecht
doaj   +1 more source

Prognostic Impact of FLT3‐ITD Allelic Ratio in AML Patients Treated With High‐Dose Anthracycline and a FLT3 Inhibitor

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The prognostic value of FLT3 internal tandem duplication (FLT3‐ITD) in acute myeloid leukemia (AML) has traditionally been stratified according to the ITD/wild‐type allelic ratio (AR) and NPM1 co‐mutation status. We evaluated the prognostic impact of FLT3‐ITD AR in 459 newly diagnosed AML patients younger than 60 years enrolled in the ...
Mathieu Leclerc   +43 more
wiley   +1 more source

Introducing Christian Ethics:2nd edition

open access: yes, 2017
Introducing Christian Ethics 2e, now thoroughly revised and updated, offers an unparalleled introduction to the study of Christian Ethics, mapping and exploring all the major ethical approaches, and offering thoughtful insights into the complex moral ...
Quash, Ben; id_orcid   +2 more
core   +3 more sources

Nothing to See Here: Researching Non‐Recent Child Abuse in Schools and the Politics of Silence

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT While institutions, including schools, have responsibilities to protect children from harm, responses to instances of child sexual abuse have often exhibited avoidance and denial. Recent public inquiries in Australia revealed that some institutions, particularly in the Catholic sector, employed a deliberate strategy of silence which was used ...
John Crowley   +2 more
wiley   +1 more source

Of poetics and possibility: Richard Kearney’s post-metaphysical God

open access: yesHTS Teologiese Studies/Theological Studies, 2017
This article provides an overview of Richard Kearney’s attempt at re-imagining God post-metaphysically. In the context of a continental dialogue on the topic, Kearney has responded to onto-theology with a hermeneutic and phenomenologically informed ...
Yolande Steenkamp
doaj   +1 more source

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

open access: yesAngewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber   +21 more
wiley   +1 more source

Christian ethics in love

open access: yesRUDN Journal of Philosophy, 2013
Author of this article comes to the conclusion that in a culture of consumption Christian concept of love has not lost its relevance. Love as the base value is the basis of 12-step program of Alcoholics Anonymous, which is formed on the basis of the ...
S A Lohov
doaj  

A dialogue with Sen’s Theory of capabilities and its implications for our National Democratic Revolution

open access: yesHTS Teologiese Studies/Theological Studies, 2016
In ‘traditional’ liberation theological discourse, especially the Latin American strand, the concept of development, desarrollismo, that is developmentalism, has been severely critiqued.
Vuyani Vellem
doaj   +1 more source

The case for theological ethics: an appreciation of Ernil Brunner and Reinhold Niebuhr as moral theologians [PDF]

open access: yes, 1990
The purpose of this thesis is to test the hypothesis that Christian ethics is not merely a department of general ethics, but is essentially theological.
Hamlyn, Eric Crawford
core  

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