Results 51 to 60 of about 38,527 (251)

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

Short-Term Immunosuppression Enhances Long-Term Survival of Bovine Chromaffin Cell Xenografts in Rat Cns

Cell Transplantation, 1992
Xenogeneic donors, a largely untapped resource, would solve many of the problems associated with the limited availability of human donor tissue for neural transplantation.
John D. Ortega, Jacqueline Sagen, George D. Pappas   +2 more
doaj   +1 more source

Schwann Cell Precursors Generate the Majority of Chromaffin Cells in Zuckerkandl Organ and Some Sympathetic Neurons in Paraganglia

Frontiers in Molecular Neuroscience, 2019
In humans, neurosecretory chromaffin cells control a number of important bodily functions, including those related to stress response. Chromaffin cells appear as a distinct cell type at the beginning of midgestation and are the main cellular source of ...
Maria Eleni Kastriti, Maria Eleni Kastriti, Polina Kameneva, Polina Kameneva, Dmitry Kamenev, Dmitry Kamenev, Viacheslav Dyachuk, Viacheslav Dyachuk, Alessandro Furlan, Marek Hampl, Marek Hampl, Fatima Memic, Ulrika Marklund, Francois Lallemend, Saida Hadjab, Laura Calvo-Enrique, Patrik Ernfors, Kaj Fried, Igor Adameyko, Igor Adameyko   +19 more
doaj   +1 more source

α-Toxin permeabilized rat pheochromocytoma cells [PDF]

, 1985
The channel forming α-toxin of Staphylococcus aureus (about 50 μg/ml) markedly reduces the Ca2+ requirement for dopamine release by the rat pheochromocytoma cell line (PC 12).
Baker, Bhakdi, Brooks, Dunn, Flodgaard, Füssle, Gratzl, Greene, Greene, Knight, Knight, Sillen, Wilson   +12 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Cyclic ADP-Ribose Requires FK506-Binding Protein to Regulate Intracellular Ca2+ Dynamics and Catecholamine Release in Acetylcholine-Stimulated Bovine Adrenal Chromaffin Cells

Journal of Pharmacological Sciences, 2006
.: The present study was undertaken to elucidate whether cyclic ADP-ribose (cADPR) mediates the amplification of Ca2+ signaling and catecholamine release via the involvement of FK506-binding proteins (FKBPs)/ryanodine receptor (RyR) in bovine adrenal ...
Morita Katsuya, Kitayama Tomoya, Kitayama Shigeo, Dohi Toshihiro   +3 more
doaj   +1 more source

Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]

, 1992
1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G., Gratzl, Manfred, Rosenthal, W., Spicher, K., Stecher, B., Wegenhorst, U.   +5 more
core  

Prognostic Value of a Histopathological Scoring System and the Ki67 Proliferation Index in Dogs With Phaeochromocytoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine phaeochromocytomas (PCCs) are neuroendocrine tumours with malignant potential. Metastatic disease remains the sole definitive evidence of malignancy. Histopathological criteria to predict long‐term survival have not been established in dogs.
Marit F. van den Berg, Aitor Martínez Ruiz, Maurice M. J. M. Zandvliet, Sebastiaan A. van Nimwegen, Hans S. Kooistra, Sara Galac, Guy C. M. Grinwis   +6 more
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Differentiation of Chromaffin Progenitor Cells to Dopaminergic Neurons

Cell Transplantation, 2012
The differentiation of dopamine-producing neurons from chromaffin progenitors might represent a new valuable source for replacement therapies in Parkinson's disease.
Vladimir Vukicevic, Janine Schmid, Andreas Hermann, Sven Lange, Nan Qin, Linda Gebauer, Kuei-Fang Chung, Ursula Ravens, Graeme Eisenhofer, Alexander Storch, Marius Ader, Stefan R. Bornstein, Monika Ehrhart-Bornstein Ph.D.   +12 more
doaj   +1 more source