Results 121 to 130 of about 496,209 (318)

Figure S3 from AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells [PDF]

, 2023
Guangyan Sun, Guy J. Leclerc, Sanjay Chahar, Julio C. Barredo   +3 more
openalex   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Comparison of spatial transcriptomics technologies using tumor cryosections

Genome Biology
Background Spatial transcriptomics technologies are revolutionizing our understanding of intra-tumor heterogeneity and the tumor microenvironment by revealing single-cell molecular profiles within their spatial tissue context.
Anne Rademacher, Alik Huseynov, Michele Bortolomeazzi, Sina Jasmin Wille, Sabrina Schumacher, Pooja Sant, Denise Keitel, Konstantin Okonechnikov, David R. Ghasemi, Kristian W. Pajtler, Jan-Philipp Mallm, Karsten Rippe   +11 more
doaj   +1 more source

Referee report. For: Analysis of distribution of chromatin marks across "divergence islands" in three-spined stickleback (Gasterosteus aculeatus) [version 1; referees: 2 approved with reservations]

, 2017
Ilkka Kronholm
openalex   +1 more source

Femtosecond‐Laser‐Fabricated 3D CYTOP Microfluidic Chips Enabling Super‐Resolution Live Imaging of Cell Behavior in Confined Microspaces

Advanced Materials Technologies, EarlyView.
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka, Mirai Hanzawa, Kotaro Obata, Sota Matsumoto, Masatoshi Takagi, Asako Sakaue‐Sawano, Asako Tosaki, Satoshi Shimozono, Felix Sima, Hiroyuki Kawano, Takuro Tojima, Daisuke Miyashiro, Kazunari Ozasa, Yasutaka Hanada, Godai Miyaji, Akihiko Nakano, Atsushi Miyawaki   +16 more
wiley   +1 more source

Case Report: SMARCA4-deficient NSCLC with brain metastasis harboring co-mutations in chromatin remodeling and DNA damage repair pathways [PDF]

Ji‐Joon Song, Shikun Yang, Xia Lei
openalex   +1 more source

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

Advanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin, Sayba Z. Chowdhury, Maurice de Wit, Rania Head, Kiki Bals, Erwin Brosens, Marvin M. van Luijn, Hayri E. Balcioglu, Angelo Accardo, Pim J. French   +9 more
wiley   +1 more source

Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data [PDF]

Ruitong Li, Jean-Baptiste Alberge, Tina Keshavarzian, Junko Tsuji, Johan E. Gustafsson, Mahshid Rahmat, Elizabeth D. Lightbody, Stephanie Deng, Santiago Riviero, Mendy Miller, F Naz Cemre Kalayci, Adrian Wiestner, Clare Sun, Mathieu Lupien, Irene M. Ghobrial, Erin M. Parry, Teng Gao, Gad Getz   +17 more
openalex   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Analysis of β-globin Chromatin Micro-Environment Using a Novel 3C Variant, 4Cv

, 2010
Ryan Pink, Christopher H. Eskiw, Daniel P. Caley, David R. F. Carter   +3 more
openalex   +2 more sources