Results 191 to 200 of about 452,870 (322)

CYTOLOGICAL OBSERVATIONS ON THE CHROMATIN BODIES OF TWO BACILLUS SPECIES [PDF]

, 1962
Bishwanath Chatterjee, Robert P. Williams   +1 more
openalex   +1 more source

Unveiling chromatin dynamics with virtual epigenome. [PDF]

Nat Commun
Lin MY, Lo YC, Hung JH.
europepmc   +1 more source

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

The use of polyethylenesulphonate in the fractionation of proteins and some aspects of its application to the separation of chromatin proteins [PDF]

, 1969
R Krauze, A J MacGilivray, John Paul
openalex   +1 more source

H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma. [PDF]

Epigenetics Chromatin
Bhattarai S, Hakkim FL, Day CA, Grigore F, Langfald A, Entin I, Hinchcliffe EH, Robinson JP.   +7 more
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

The Association of a Metabolite of Vitamin D3 with Intestinal Mucosa Chromatin in Vivo

, 1968
Mark R. Haussler, James F. Myrtle, Anthony W. Norman   +2 more
openalex   +1 more source

Eosinophil cytolysis with or without ETosis in four cases of human gastric cancer: a comparative ultrastructural study. [PDF]

Explor Target Antitumor Ther
Caruso R, Caruso V, Rigoli L.
europepmc   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source

ACTIVE AND INACTIVE REGIONS OF NUCLEAR CHROMATIN AS REVEALED BY ELECTRON MICROSCOPE AUTORADIOGRAPHY

, 1964
Virginia C. Littau, V. G. Allfrey, John H. Frenster, A. E. Mirsky   +3 more
openalex   +1 more source