Results 201 to 210 of about 496,209 (318)
Pan-cistrome analysis of the leaf accessible chromatin regions of 214 maize inbred lines [PDF]
Yongli Zhu +12 more
openalex +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Spatial Chromatin Organization Across the Cell Cycle: Insights from Auxin-Inducible Protein Depletion. [PDF]
Nurislamov A, Yunusova A.
europepmc +1 more source
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Multi-omic relay velocity modeling uncovers dynamic chromatin-transcription regulation across cell states. [PDF]
Hong A, Lee S, Kim K.
europepmc +1 more source
Chromatin Template Activity and Chromatin Structure
R, Axel, H, Cedar, G, Felsenfeld
openaire +2 more sources
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao +13 more
wiley +1 more source
Mitochondria and Epigenetic Regulation: Bidirectional Crosstalk and Emerging Mitochondria-Targeted Degron Tools. [PDF]
Xu Y +6 more
europepmc +1 more source

