Results 201 to 210 of about 452,870 (322)

A survey of sex chromatin abnormalities in mental hospitals. [PDF]

, 1968
N. Maclean, W.M. Court Brown, P.A. Jacobs, David Mantle, J.A. Strong   +4 more
openalex   +1 more source

Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors. [PDF]

Epigenetics Chromatin
Ma Y, Li C, Valente S.
europepmc   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

Advanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu, Qing Ma, Yunhui Kong, Zhaoyue Wang, Minglu Xu, Xiangyi Chen, Yajuan Su, Tinghui Xiao, Qing He, Xuan Wang, Wenjun Xu, Yiling Yang, Xushu Wang, Xiaobo Li, Yanfang Liu, Shuangshuang Chen, Rui Zhao, Meng Guo, Gaowei Wang, Weida Li   +19 more
wiley   +1 more source

The role of chromatin in estrogen action in the uterus, I. The control of template capacity and chemical composition and the binding of H3-estradiol-17 beta.

, 1968
C S Teng, T H Hamilton
openalex   +1 more source

Chromatin structures from integrated AI and polymer physics model. [PDF]

PLoS Comput Biol
Schultz ER, Kyhl S, Willett R, de Pablo JJ.   +3 more
europepmc   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Testosterone Production in Chromatin-Positive Klinefelter's Syndrome [PDF]

, 1965
Mortimer B. Lipsett, Thomas E. Davis, Hildegard Wilson, Craig J. Canfield   +3 more
openalex   +1 more source

Conservation of dichromatin organization along regional centromeres. [PDF]

Cell Genom
Dubocanin D, Hartley GA, Sedeño Cortés AE, Mao Y, Hedouin S, Ranchalis J, Agarwal A, Logsdon GA, Munson KM, Real T, Mallory BJ, Eichler EE, Biggins S, O'Neill RJ, Stergachis AB.   +14 more
europepmc   +1 more source

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

Advanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan, Xueman Chen, Huai Yu, Jianzhao Ruan, Jingliang Kang, Xiaoyu Nie, Yumei Cao, Su'an Tang, Changhai Ding   +8 more
wiley   +1 more source

DNA Sequence Changes Resulting from Codon Optimization Affect Gene Expression in <i>Pichia pastoris</i> by Altering Chromatin Accessibility. [PDF]

J Fungi (Basel)
Lu C, Guo L, Fang B, Shi J, Zhou M.
europepmc   +1 more source