Results 201 to 210 of about 995,221 (398)
ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide
Jason D. Buenrostro+3 more
semanticscholar +1 more source
ISOLATION AND CHARACTERIZATION OF CHROMATIN FROM NEUROSPORA CRASSA [PDF]
R.S. Dwivedi+2 more
openalex +1 more source
Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang+8 more
wiley +1 more source
The Role of Chromatin during Transcription
Bing Li, M. Carey, J. Workman
semanticscholar +1 more source
Chromatin Template Activity and Chromatin Structure
Howard Cedar+2 more
openaire +3 more sources
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin+9 more
wiley +1 more source
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang+9 more
wiley +1 more source
ChromHMM: automating chromatin-state discovery and characterization
J. Ernst, Manolis Kellis
semanticscholar +1 more source