Results 211 to 220 of about 392,110 (289)
Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation
Advanced Science, EarlyView.Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu +9 more
wiley +1 more source
Analysis of histone in situ in developmentally inactivated chromatin.
, 1965 Laurence Berlowitz
openalex +1 more source
Testosterone Production in Chromatin-Positive Klinefelter's Syndrome [PDF]
, 1965 Mortimer B. Lipsett +3 more
openalex +1 more source
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
The Sex Chromatin of Interphase Nuclei in Platyrrhine Monkeys
, 1962 Margaret M. Beath, Kurt Benirschke
openalex +2 more sources
Finger and palm prints in chromatin-positive males. [PDF]
, 1968 Henry Hunter
openalex +1 more source
Advanced Science, EarlyView.This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu +19 more
wiley +1 more source
A histological study of chromatin positive and negative hydatidiform moles.
, 1969 Y.W. Loke, R. Borland
openalex +1 more source
Primary Embryonal Sex Ratio in Normal Pregnancies determined by the Nuclear Chromatin [PDF]
, 1961 F.E. Szontágh, A Jakobovits, CH. MÉHES
openalex +1 more source
Advanced Science, EarlyView.Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu +12 more
wiley +1 more source