Results 251 to 260 of about 971,786 (390)

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena. [PDF]

Epigenetics Chromatin
Garg J, Saettone A, Nabeel-Shah S, Dang S, Khalid AH, Loehr J, Petrova A, Burns JD, Karabatsos P, Shibin S, Wahab S, Taverna SD, Greenblatt JF, Lambert JP, Fillingham J.   +14 more
europepmc   +1 more source

A survey of sex chromatin abnormalities in mental hospitals. [PDF]

, 1968
N. Maclean, W.M. Court Brown, P.A. Jacobs, David Mantle, J.A. Strong   +4 more
openalex   +1 more source

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response. [PDF]

Mol Metab
de Smalen LM, Adak V, Leuchtmann AB, Schneider-Heieck K, Steurer SA, Handschin C.   +5 more
europepmc   +1 more source

Circular ecDNA promotes accessible chromatin and high oncogene expression

Nature, 2019
Sihan Wu, Kristen M. Turner, Nam Nguyen, R. Raviram, M. Erb, J. Santini, J. Luebeck, Utkrisht Rajkumar, Yarui Diao, Yarui Diao, Bin Li, Wenjing Zhang, Nathan M. Jameson, M. Corces, Jeffrey M. Granja, Xingqi Chen, Xingqi Chen, C. Coruh, Armen Abnousi, Jack Houston, Z. Ye, Rong Hu, Miao Yu, Hoon Kim, Julie A. Law, R. Verhaak, Ming Hu, F. Furnari, Howard Y. Chang, Howard Y. Chang, B. Ren, V. Bafna, P. Mischel   +32 more
semanticscholar   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

Advanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang   +6 more
wiley   +1 more source

Nucleosome spacing can fine-tune higher-order chromatin assembly. [PDF]

Nat Commun
Chen L, Maristany MJ, Farr SE, Luo J, Gibson BA, Doolittle LK, Espinosa JR, Huertas J, Redding S, Collepardo-Guevara R, Rosen MK.   +10 more
europepmc   +1 more source

The role of chromatin in estrogen action in the uterus, I. The control of template capacity and chemical composition and the binding of H3-estradiol-17 beta.

, 1968
C S Teng, T H Hamilton
openalex   +1 more source

An Antagonism Between Ethylene Signaling and DNA Methylation Orchestrates the Progression of Leaf Senescence in Non‐heading Chinese Cabbage

Advanced Science, EarlyView.
CMT2 mediates the maintenance of DNA methylation on the promoters of SAGs, thereby inhibiting EIN3A untimely activating SAGs’ expression. Aging‐impelled striking upregulation of EIN3A strongly suppresses the expression of CMT2 to reduce the methylation level, which releases the activation of EIN3A on SAGs, thus initiating and accelerating the ...
Dingyu Zhang, Yong Luo, Han Wang, Xiaofeng Li, Liming Miao, Lu Gao, Haibo Hao, Xinman Wang, Benke Kuai, Hongfang Zhu, Guodong Ren   +10 more
wiley   +1 more source