Results 261 to 270 of about 452,870 (322)

Origins, Dispersal, and Impact: Bidirectional Introgression Between Chinese and European Pig Populations

Advanced Science, EarlyView.
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu, Langqing Liu, Min Huang, Donglin Ruan, Rongrong Ding, Zebin Zhang, Enqin Zheng, Shiyuan Wang, Shaoxiong Deng, Xianglun Meng, Xinyan Cheng, Jiaxin Shi, Yingshan Yang, Fuchen Zhou, Sixiu Huang, Huaqiang Yang, Zicong Li, Gengyuan Cai, Zhenfang Wu, Jie Yang   +19 more
wiley   +1 more source

Electron microscopic and biochemical evidence that chromatin structure is a repeating unit

, 1975
P Oudet, M. Gross-Bellard, Pierre Chambon   +2 more
openalex   +1 more source

Fibroblast atlas: Shared and specific cell types across tissues. [PDF]

Sci Adv
Liu K, Cui Y, Han H, Guo E, Shi X, Xiong K, Zhang N, Zhai S, Sang S, Liu M, Chen B, Gu Y.   +11 more
europepmc   +1 more source

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

Extracts of Drosophila embryos mediate chromatin assembly in vitro.

, 1979
Timothy Nelson, T S Hsieh, Douglas L. Brutlag   +2 more
openalex   +1 more source

Copy number normalization distinguishes differential signals driven by copy number differences in ATAC-seq and ChIP-seq. [PDF]

BMC Genomics
Su D, Peters M, Soltys V, Chan YF.
europepmc   +1 more source

Wnt Inhibition Safeguards Porcine Embryonic Stem Cells From the Acquisition of Extraembryonic Endoderm Cell Fates

Advanced Science, EarlyView.
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang, Liang Zhong, Zhuangfei Wang, Jinzhu Xiang, Duanqing Pei   +4 more
wiley   +1 more source

Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer. [PDF]

Front Genet
Saw AK, Madhok A, Bhattacharya A, Nandi S, Galande S.   +4 more
europepmc   +1 more source

Ethylene‐Activated E3 Ubiquitin Ligase MdEAEL1 Promotes Apple Fruit Softening by Facilitating the Dissociation of Transcriptional Repressor Complexes

Advanced Science, EarlyView.
Ethylene‐activated MdEAEL1 mediates the disassembly of the MdZFP3‐MdTPL4‐MdHDA19 transcriptional repression complex, upregulating the histone acetylation levels in the promoter regions of cell wall degradation‐related genes, consequently promoting softening during storage.
Tong Li, Li Liu, Guangxin Yang, Yingcong Cai, Yingda Wang, Bowen Sun, Le Sun, Weiting Liu, Aide Wang   +8 more
wiley   +1 more source

Chromatin landscape in paired human visceral and subcutaneous adipose tissue and its impact on clinical variables in obesity. [PDF]

EBioMedicine
Saeed S, la Cour Poulsen L, Visnovska T, Hoffmann A, Ghosh A, Wolfrum C, Rønningen T, Dahl MB, Wang J, Cayir A, Mala T, Kristinsson JA, Svanevik M, Hjelmesæth J, Hertel JK, Blüher M, Valderhaug TG, Böttcher Y.   +17 more
europepmc   +1 more source