Results 301 to 310 of about 971,786 (390)

Double minute chromatin bodies in a sub-ependymal glioma

, 1968
Kiran Kucheria
openalex   +2 more sources

Inhibition of UBE2C Promotes Parkin‐Mediated K63‐Linked Ubiquitination of TOP2A to Induce Senescence and Increase Sensitivity of Doxorubicin in Breast Cancer

Advanced Science, EarlyView.
In the study, UBE2C was found to be significantly overexpressed in breast cancer and transcriptionally regulated by FOXM1. Inhibition of UBE2C suppressed proliferation, induced senescence, and sensitized breast cancer cells to doxorubicin. Mechanistically, UBE2C inhibition promoted Parkin‐mediated K63‐linked ubiquitination of TOP2A.
Yihui Yang, Wan Li, Hong Yang, Fang Xu, Sen Zhang, Wanxin Cao, Xiaoxue Li, Xu Zhang, Xiangyin Chi, Hongquan Wang, Guanhua Du, Yumin Wang, Jinhua Wang   +12 more
wiley   +1 more source

Combinatorial profiling of multiple histone modifications and transcriptome in single cells using scMTR-seq. [PDF]

Sci Adv
Wang Y, Li J, Malcolm AA, Mansfield W, Clark SJ, Argelaguet R, Biggins L, Acton RJ, Andrews S, Reik W, Kelsey G, Rugg-Gunn PJ.   +11 more
europepmc   +1 more source

The Sex Chromatin of Interphase Nuclei in Platyrrhine Monkeys

, 1962
Margaret M. Beath, Kurt Benirschke
openalex   +2 more sources

A unique chromatin signature uncovers early developmental enhancers in humans

Nature, 2011
Á. Rada-Iglesias, R. Bajpai, T. Swigut, S. Brugmann, Ryan A. Flynn, J. Wysocka   +5 more
semanticscholar   +1 more source

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

Advanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye, Shi Li, Guofang Bi, Binghui Li, Zhai Cai, Meixian Jin, Ying Zhang, Wanren Yang, Yang Li, Shao Li, Wei Hu, Yi Gao, Mingxin Pan, Shuqin Zhou, Chao Zhang, Huichang Bi, Qing Peng   +16 more
wiley   +1 more source

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Cell, 2010
Sreenath V. Sharma, Diana Y. Lee, Bihua Li, M. P. Quinlan, F. Takahashi, S. Maheswaran, U. McDermott, N. Azizian, L. Zou, M. Fischbach, Kwok-kin Wong, K. Brandstetter, Ben S. Wittner, Sridhar Ramaswamy, M. Classon, J. Settleman   +15 more
semanticscholar   +1 more source

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Dynamics of chromatin accessibility governing Gd-IgA1 synthesis in B cells associated with IgA nephropathy. [PDF]

Exp Mol Med
Gan Y, Li J, Li W, Han Q, Zhang R, Yu H, Zeng W, Qing F, Luo M, Li H, Yang Q.   +10 more
europepmc   +1 more source

Study on the Sex Chromatin in Oral Exfoliated Cells

, 1963
Masayoshi Nakatani
openalex   +2 more sources