Results 351 to 360 of about 995,221 (398)
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Current Opinion in Cell Biology, 2013
Signaling involves the coordinated action of multiple molecules including stimuli, receptors and enzymes part of which interact with the transcriptional machinery and target chromatin. Signaling systems regulate the cell events responsible for survival, development and homeostasis.
Tamaki Suganuma, Jerry L. Workman
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Signaling involves the coordinated action of multiple molecules including stimuli, receptors and enzymes part of which interact with the transcriptional machinery and target chromatin. Signaling systems regulate the cell events responsible for survival, development and homeostasis.
Tamaki Suganuma, Jerry L. Workman
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Nature New Biology, 1971
Physico-chemical experiments show that histones are not evenly distributed in chromatin. About half of the DNA is “open” and not covered with proteins.
R. J. Clark, Gary Felsenfeld
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Physico-chemical experiments show that histones are not evenly distributed in chromatin. About half of the DNA is “open” and not covered with proteins.
R. J. Clark, Gary Felsenfeld
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The FASEB Journal, 1996
The compaction of DNA into chromatin in the eukaryotic nucleus poses many obstacles to transcription. Individual nucleosomes as well as higher order structures limit access of cis-acting regulatory elements to trans-acting factors. The structural nature of this inhibition and the mechanisms by which chromatin is remodeled to facilitate the regulation ...
Diane G. Edmondson, Sharon Y. Roth
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The compaction of DNA into chromatin in the eukaryotic nucleus poses many obstacles to transcription. Individual nucleosomes as well as higher order structures limit access of cis-acting regulatory elements to trans-acting factors. The structural nature of this inhibition and the mechanisms by which chromatin is remodeled to facilitate the regulation ...
Diane G. Edmondson, Sharon Y. Roth
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Nature, 2012Jeremy A Schwartzentruber +2 more
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International Journal for Parasitology, 1994
The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
W. Schlimme +4 more
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The nuclear chromatin of trypanosomes is organised in the form of nucleosome filaments. When soluble chromatin is prepared under suitable conditions, a regular array of nucleosomes can be shown by electron microscopy. Chromatin of blood stream as well as procyclic culture forms of Trypanosoma brucei brucei and of T.
W. Schlimme +4 more
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The European Physical Journal E, 2006
Nucleosome is the basic subunit of the chromatin, which organizes the genomic DNA within the cell nucleus. It was understood in the last decade that beside the DNA compaction it plays an important role in the regulation of the gene expression. In its intact form, the nucleosome represents an important mechanical barrier and, among others, it prevents ...
J. Bednar, C. Claudet
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Nucleosome is the basic subunit of the chromatin, which organizes the genomic DNA within the cell nucleus. It was understood in the last decade that beside the DNA compaction it plays an important role in the regulation of the gene expression. In its intact form, the nucleosome represents an important mechanical barrier and, among others, it prevents ...
J. Bednar, C. Claudet
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Hybrids in the chromatin [PDF]
Nature Plants, 2017 New genomic maps reveal that R-loop structures formed upon hybridization of nascent RNA transcripts to the DNA template are a common characteristic of Arabidopsis chromatin that may have a broad impact on gene expression.
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Critical Reviews in Biochemistry, 1983
(1983). The Folding of Chromatin. Critical Reviews in Biochemistry: Vol. 15, No. 1, pp. 57-91.
Donald M. Crothers, P. J. G. Butler
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(1983). The Folding of Chromatin. Critical Reviews in Biochemistry: Vol. 15, No. 1, pp. 57-91.
Donald M. Crothers, P. J. G. Butler
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Immunoprecipitation of chromatin
1996Publisher Summary This chapter discusses the immunoprecipitation of chromatin. The chapter discusses three standard protocols, all of which are used to analyze the role of specific proteins within defined regions of the eukaryotic genome. It analyzes both the DNA and the protein after immunoprecipitation.
Bryan M. Turner, Laura P. O'Neill
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Nature Structural & Molecular Biology, 2007 To accompany the Focus on Chromatin appearing in this issue of Nature Structural & Molecular Biology, a series of primers has been specially prepared that covers the wealth of knowledge in four areas of chromatin research. These areas include functions associated with covalent histone modifications, the enzymes that mediate these modifications, modules
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