Results 121 to 130 of about 411,650 (265)
Copper(I)-Catalyzed Stereoselective Synthesis of 4‑(Aminomethylene)-1,4-dihydroisoquinolin-3-ones from 4‑Diazo-1,4-dihydroisoquinolin-3-ones and Thioamides. [PDF]
Wang Y +5 more
europepmc +1 more source
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou +21 more
wiley +1 more source
Do softgel manufacturing or gastric conditions break down carrageenan into poligeenan? [PDF]
Jin SA, Fang Q, Sukuru K.
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Gel-filtration chromatography is a popular and versatile technique that permits the effective separation of proteins and other biological molecules in high yield. Here, the basis of the method is described and typical matrix types are contrasted. The selection of suitable operating conditions and applications of the method are also discussed.
Ó Fágáin, Ciarán +2 more
openaire +1 more source
Extraction and Isolation of Extracellular Vesicles From <i>Piper betle</i> Leaves Using the Apoplastic Fluid Washing and Size Exclusion Chromatography Method. [PDF]
Sanddy I +6 more
europepmc +1 more source
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun +7 more
wiley +1 more source
Mitochondrial super complexes in the colorless chlorophycean alga Polytomella parva. [PDF]
Ostolga-Chavarría M +5 more
europepmc +1 more source

