Results 131 to 140 of about 1,583,880 (361)

Chemical and toxicological analysis of zolpidem

RUDN Journal of Medicine, 2009
Methods for measuring zolpidem are suggested: thin-layer chromatography, high-pressure liquid chromatography, ultrtaviolet spectrophotometry, gas chromatography with mass selective detector can be used for identification zolpidem in chemical ...
Y A Khomov, E I Egorova, N V Koksharova, E A Shilova   +3 more
doaj  

Clinical application of blood concentration monitoring of active metabolite of oxcarbazepine in childhood focal epilepsy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To investigate the value of blood concentration monitoring of 10-monohydroxy carbamazepine (MHD), the active metabolite of oxcarbazepine (OXC), in the treatment ofchildhood focal epilepsy.
Pei-yuan ZHANG, Hui-fen2 LI, Xiao-jun LIU, Xiao-li YU, Yu-qin ZHANG   +4 more
doaj   +1 more source

Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction [PDF]

, 2002
Quantification of the new immunosuppressant sirolimus (syn. rapamycin; Rapamune((R))) in whole blood by chromatography is essential for its clinical use since no immunoassay is available although monitoring is mandatory.
Fleischer, Claudia, Groetzner, Jan, Meiser, Bruno, Seidel, Dietrich, Spöhrer, Ute, Vogeser, Michael   +5 more
core   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels

Advanced Functional Materials, EarlyView.
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco, Marc Falandt, Myriam Neumann, Martina Viola, Thibault Sampon, Marta G. Valverde, Anne Metje van Genderen, Silvia M. Mihaila, Cornelus F. van Nostrum, Bas G. P. van Ravensteijn, Riccardo Levato, Rosalinde Masereeuw, Tina Vermonden   +12 more
wiley   +1 more source

The separation of sterol intermediates in cholesterol biosynthesis by high pressure liquid chromatography

Journal of Lipid Research, 1980
A three-step procedure has been developed for the separation of complex mixtures of sterol intermediates in cholesterol biosynthesis. The method has been applied to the separation of sterol intermediates formed from [14C]mevalonate by normal rat ...
E Hansbury, T J Scallen
doaj  

Structure of murine Ia antigens. Two dimensional electrophoretic analyses and high pressure liquid chromatography tryptic peptide maps of products of the I-A and I-E subregions and of an associated invariant polypeptide

Journal of Experimental Medicine, 1981
We demonstrate that an invariant polypeptide, first described by Jones et al. (21), co-immunoprecipitates with our Ia molecules, that its interaction with Ia polypeptides varies with haplotype, and that it is not a precursor of the Aalpha, Abeta, Ealpha,
M. Mcmillan, J. Frelinger, P. Jones, D. Murphy, H. Mcdevitt, L. Hood   +5 more
semanticscholar   +1 more source

Investigating the Structure–Function Relationships of Fluorinated Interfaces for PFAS Capture and Electrochemically‐Mediated Release

Advanced Functional Materials, EarlyView.
This study explores the use of fluorinated copolymers with varying fluorophilic side chain lengths to enhance PFAS affinity. The integration of electrochemical techniques demonstrates enhanced adsorbent regeneration, with molecular dynamics simulations providing insight into the molecular‐level interactions involved.
Anaira Román Santiago, Adrija Dutta, Jhen‐Cih Wu, Song Yin, Ye Won Lee, Chia‐Hung Hou, Diwakar Shukla, Xiao Su   +7 more
wiley   +1 more source

Characterization and toxicity evaluation of degradation products of febantel

Future Journal of Pharmaceutical Sciences, 2020
Background The aim of the present work was to determine potential toxicity of degradation products of febantel generated under different stress conditions mentioned in guideline Q1A (R2) laid down by International Council for Harmonization (ICH).
Anand A. Mahajan, Amey M. Marathe, Suvarna S. Jarande, Raghuvir Pissurlenkar, Vandana T. Gawande   +4 more
doaj   +1 more source

Determination of carbohydrates in infant milk powders by ultra-performance liquid chromatography with evaporative light scattering detector and BEH HILIC column [PDF]

arXiv, 2017
The possibility of carbohydrate separation in BEH HILIC (Ethylene Bridged Hybride, Hydrophilic Interaction Liquid Chromatography) column was studied by ultra-performance liquid chromatography (UPLC) with evaporative light scattering detector (ELSD) and mobile phase containing amine compounds as modifiers.
arxiv