Results 181 to 190 of about 370,485 (298)

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Fraction collection of bioactive compounds from ion chromatography: No longer mission impossible. [PDF]

open access: yesMethodsX
Yates HSA   +5 more
europepmc   +1 more source

Ion-Exchange Paper Chromatography [PDF]

open access: yesProceedings of the Association of Clinical Biochemists, 1963
openaire   +2 more sources

Reversible High-Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation. [PDF]

open access: yesAdv Sci (Weinh)
Shi C   +9 more
europepmc   +1 more source

Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof

open access: yesAngewandte Chemie International Edition, Accepted Article.
Phosphorylation plays important roles in biology by modulating the structure, reactivity, and biological function of a broad range of molecules. Biocatalytic phosphorylation has attracted attention from synthetic chemists due to its selectivity and mild reaction conditions using ATP as a phosphate donor. Given the potential synthetic utility of kinases
Ahram Kim   +8 more
wiley   +1 more source

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