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Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Technologies for large‐scale manufacturing of viral vectors for gene therapies, such as tangential flow filtration and membrane chromatography, are under development. In these early stages of process development, techno‐economic analyses are useful for identifying membrane properties yielding the greatest impact on process performance. In this
Juan J. Romero, Eleanor W. Jenkins, Jacob I. Monroe, S. Ranil Wickramasinghe, Xianghong Qian, Dibakar Bhattacharyya, Scott M. Husson   +6 more
wiley   +1 more source

The Enrichment of Acetic Acid Using an Integrated Reverse Osmosis-Electrodialysis Process. [PDF]

Membranes (Basel)
Xu S, Zhang L, Zhang Z, Xie L, Zhang W.
europepmc   +1 more source

Impact of Mobile Phase Composition on Separation Selectivity of Labeled Dextran Ladder in Hydrophilic Interaction Liquid Chromatography. [PDF]

Molecules
Grčman M, Pompe NR, Kočar D, Pompe M.
europepmc   +1 more source

Isoniazid-Modified Silica for Hydrophilic Interaction Chromatography and as an Adsorbent for Dye Removal in Wastewater Samples. [PDF]

ACS Omega
Mallik AK, Anik MT, Rösler J, Meckelmann SW, Schmitz OJ.   +4 more
europepmc   +1 more source

Development of a permethylation-based detection method for oligo/polysialic acid structures via tandem MALDI-TOF mass spectrometry. [PDF]

BBA Adv
Suzuki K, Wu D, Kitajima K, Yamakawa N, Omoto T, Hane M, Sato C.   +6 more
europepmc   +1 more source

Cloning and expression of chromate reductase from Bacillus paramycoides S48 for chromium remediation. [PDF]

Sci Rep
Kalsoom K, Din SU, Ceylan E, Hasan F, Khan S, Badshah M, Çanakçi S, Belduz AO, Shah AA.   +8 more
europepmc   +1 more source

Diagnosis of hemogobinopathies in the clinical laboratory: an occult Hofu hemoglobin on HPLC. [PDF]

Adv Lab Med
Urroz ME, Delgado AIL, Conejero RO, Nistal DÁ.   +3 more
europepmc   +1 more source

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Ion-exchange chromatography for the characterization of biopharmaceuticals

Journal of Pharmaceutical and Biomedical Analysis, 2015
Ion-exchange chromatography (IEX) is a historical technique widely used for the detailed characterization of therapeutic proteins and can be considered as a reference and powerful technique for the qualitative and quantitative evaluation of charge heterogeneity.
Fekete, Szabolcs, Beck, Alain, Veuthey, Jean-Luc, Guillarme, Davy   +3 more
openaire   +5 more sources