Micellar electrokinetic capillary chromatography theory based on conventional chromatography
Journal of Chromatography A, 1993From the definitions of retention time (tR) and resolution (Rs) in conventional chromatography, two fundamental equations for the retention behaviour and resolution of neutral solutes are derived and proved to be valid in all cases of micellar electrokinetic capillary chromatography (MECC).
C X, Zhang, Z P, Sun, D K, Ling
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Determination of bis(amidinohydrazones) by micellar electrokinetic capillary chromatography
Journal of Pharmaceutical and Biomedical Analysis, 1992A micellar electrokinetic capillary chromatography method was developed for the separation and determination of aliphatic congeners of bis(amidinohydrazones) in standard solution. Eight bis(amidinohydrazones) could be determined in less than 15 min at an applied voltage of 22 kV, using 0.05 M sodium phosphate as buffer (pH 7.0) together with 1 mM N ...
P, Lukkari +4 more
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Micellar electrokinetic capillary chromatography of amoxycillin and related molecules
The Analyst, 1992A micellar electrokinetic capillary chromatographic method has been developed for the qualitative assay of amoxycillin and its degradation products and clavulanic acid. Together with amoxycillin the latter acid is an important constituent in the antibiotic Augmentin.
G N, Okafo, P, Camilleri
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Serum iohexol analysis by micellar electrokinetic capillary chromatography
ELECTROPHORESIS, 2006AbstractA simple and rapid (∼4 min) method for the measurement of iohexol in serum for assessing the glomerular filtration rate is described. It is based on direct serum injection on the capillary by MEKC. The method is linear between 8 and 260 mg/L, with an RSD of peak height of 2.9%.
Zak K, Shihabi, Mark E, Hinsdale
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Analysis of Urinary Pseudouridine by Micellar Electrokinetic Capillary Chromatography
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1997We describe a capillary electrophoresis procedure, using uridine as an internal standard, for the analysis of urinary pseudouridine following solid-phase extraction. This method retains the advantages of existing chromatographic techniques but has superior resolving power and is technically less demanding.
Evans, M. D. +3 more
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Micellar electrokinetic capillary chromatography of benzodiazepines in human urine
ELECTROPHORESIS, 1994AbstractThe determination of the major urinary compounds of eight common benzodiazepines, flunitrazepam, diazepam, midazolam, clonazepam, bromazepam, temazepam, oxazepam, and lorazepam, by micellar electrokinetic capillary chromatography (MECC) is shown to be a simple and attractive approach for confirmation testing of these drugs in human urine. After
Schafroth M, Thormann W, Allemann D
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Steroid Analysis by Micellar Electrokinetic Capillary Chromatography
2003From the clinical perspective, steroids have always held a great deal of interest, since they are highly specific in their function. They do not have a general or systemic effect, but instead regulate specific physiological functions, such as sex differentiation, fetus implantation and growth, electrolyte balance, menstrual cycles, and muscle and bone ...
A A, Mohammad +2 more
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Pharmaceutical Analysis Using Micellar Electrokinetic Capillary Chromatography
Journal of Chromatographic Science, 1988The potential utility in pharmaceutical analysis of a capillary electrokinetic separation technique that employs a micellar "pseudo-stationary phase" is discussed and illustrated. Chromatograms of separations of vitamin metabolites and derivatized amino acids are presented to illustrate the high efficiency of the technique and the ability to ...
D F, Swaile +3 more
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Separation of metallothionein isoforms by micellar electrokinetic capillary chromatography
Journal of Chromatography A, 1994Current techniques for the separation and quantification of metallothionein isoforms have limited value for routine analysis. Isoforms having a similar charge have been separated successfully using reversed-phase HPLC but this technique suffers from a slow sample turnover time.
J H, Beattie, M P, Richards
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Determination of plasma heparin by micellar electrokinetic capillary chromatography
Talanta, 1998The micellar electrokinetic capillary chromatography (MECC) method is reported for the separation of heparin, and for the possibility of direct determination of free heparin in plasma. The conditions for MECC were: pH 8.5, 25 mM sodium dodecyl sulfate (SDS), 25 mM borate buffer, with a 30 cmx50 mum ID fused-silica capillary.
X M, Zhou +3 more
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