Results 41 to 50 of about 783,055 (207)
Fixed-dose combinations of an angiotensin II receptor antagonist (telmisartan) and a thiazide diuretic (hydrochlorothiazide) provide an effective antihypertensive therapy while promoting patient compliance with the convenience of once-daily single dose ...
Ștefana STĂCESCU +4 more
doaj +1 more source
A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development. [PDF]
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Tricht EV, Sänger-van de Griend CE.
europepmc +2 more sources
A rapid and sensitive micellar electrokinetic capillary chromatography method with UV photodiode-array detection was developed for the simultaneous determination of atorvastatin and ezetimibe in fixed dose drug combination.
Blanka Székely-Szentmiklósi +4 more
doaj +1 more source
Determination of some drugs by micellar electrokinetic capillary chromatography [PDF]
In contrast to capillary zone electrophoresis, micellar electrokinetic capillary chromatography can be applied to the determination of compounds that are unchanged and almost insoluble in water.
Ackermans, M.T. +5 more
core +1 more source
Chiral Micellar Electrokinetic Chromatography [PDF]
The potential of Micellar Electrokinetic Chromatography to achieve enantiomeric separations is reviewed in this article. The separation principles and the most frequently employed separation strategies to achieve chiral separations by Micellar ...
Marina Alegre, María Luisa +5 more
core +1 more source
The search for useful compounds from plants is an important research area. Traditional screening that involves isolation and identification/quantitation is tedious, time consuming, and generates a significant amount of chemical waste.
Kurt Debruille +2 more
doaj +1 more source
A large volume sample stacking (LVSS) method in micellar electrokinetic chromatography (MEKC) with diode array detector was developed for the simultaneous separation and analysis of five compounds: protocatechuic acid, protocatechuic aldehyde, caffeic ...
Lili Wang +7 more
doaj +1 more source
Ionic liquids (ILs), such as imidazoles, can be used to prevent the sorption of analytes onto the walls of the capillary. Prior works have confirmed that coating the capillary wall with a cationic layer can increase its surface stability, thereby ...
Natalia Kaczmarczyk +6 more
doaj +1 more source
The use of different generations of Starburst (pamam) dendrimers provides a new opportunity for ion-exchange electrokinetic capillary chromatography. The uniform surface charge density and the structural homogeneity of these macroelectrolytes provide ...
Patamia, Maria +21 more
core +1 more source
The first method by micellar electrokinetic chromatography (MEKC) for the determination of empagliflozin in tablets was developed and validated following the ICH guidelines.
Pauline Trindade Biscaino +4 more
doaj +1 more source

