Results 71 to 80 of about 783,055 (207)

Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections

open access: yesELECTROPHORESIS, Volume 46, Issue 11-12, Page 653-668, June 2025.
ABSTRACT Capillary electrophoresis (CE) often offers superior separation relative to chromatography for macromolecules like monoclonal antibodies (mAbs), a major pharmaceutical class. However, electropherogram baselines pose challenges that traditional chromatography algorithms cannot address, requiring complex integration processes.
Timothy Blanc   +2 more
wiley   +1 more source

Bile Salt Surfactants in Micellar Electrokinetic Capillary Chromatography: Application to Hydrophobic Molecule Separations [PDF]

open access: yes, 1990
Bile Salt surfactants are used in the micellar electrokinetic capillary chromatography (MECC) separation of various hydrophobic compounds. The use of methanol in the mobile phase allows the separation of previously intractable compounds including ...
Oldiges, Kimberly   +4 more
core   +1 more source

Capillary electrophoresis for the assay of fixed-dose combination tablets of artesunate and amodiaquine

open access: yesMalaria Journal, 2012
Background Quality control of drugs in formulations is still a major challenge in developing countries. For the quality control of artesunate and amodiaquine tablets in fixed-dose combination, only liquid chromatographic methods have been proposed in the
Amin N’Cho   +4 more
doaj   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Effects of organic modifiers on solute retention and electrokinetic migrations in micellar electrokinetic capillary chromatography

open access: yes, 1999
Influences of seven organic modifiers, including urea, methanol (MeOH), dioxane (DIO), tetrahydrofuran (THF), acetonitrile (ACN), 1-propanol (1-PrOH) and 2-propanol (2-PrOH), on the solute retention and the electrokinetic migrations in micellar ...
Zou, HF   +9 more
core   +1 more source

Determination of Nicotine in Tobacco by Chemometric Optimization and Cation-Selective Exhaustive Injection in Combination with Sweeping-Micellar Electrokinetic Chromatography

open access: yesJournal of Analytical Methods in Chemistry, 2015
Nicotine is a potent chemical that excites the central nervous system and refreshes people. It is also physically addictive and causes dependence. To reduce the harm of tobacco products for smokers, a law was introduced that requires tobacco product ...
Yi-Hui Lin   +5 more
doaj   +1 more source

Liquid Chromatographic and Capillary Electromigration Techniques for the Analysis of Azole Antifungals

open access: yesJournal of Separation Science, Volume 48, Issue 4, April 2025.
ABSTRACT Since the introduction of azoles as antifungals in 1979, they gradually gained a spotlight in both medicinal and industrial fields. Other than being the leading antifungal medicinal drug agents, azoles have also been a major pesticide in agricultural industry.
Tuuliina Tuominen   +3 more
wiley   +1 more source

Recent Advances in Bioanalysis of Cephalosporins Toward Green Sample Preparation

open access: yesJournal of Separation Science, Volume 48, Issue 2, February 2025.
ABSTRACT This review highlights recent advances in the bioanalysis of cephalosporins using liquid chromatographic methods, focusing on green sample preparation (GSP) techniques. Cephalosporins, a class of β‐lactam antibiotics, are critical in combating bacterial infections but present challenges related to drug resistance and toxicity.
Maria Kousi   +2 more
wiley   +1 more source

MECCSIM, training software for micellar electrokinetic capillary chromatography [PDF]

open access: yes, 1995
A training simulation program for micellar electrokinetic capillary chromatography was developed. The software provides a high speed of calculation, visual detail and model accuracy with a user-friendly interface.
Hutta, M., Reijenga, J.C.
core   +1 more source

The Dawning Era of Anticancer Nanomedicines: From First Principles to Application of Silk Nanoparticles

open access: yesAdvanced Therapeutics, Volume 8, Issue 1, January 2025.
This review evaluates the achievements and limitations of the anticancer silk nanomedicine field. Silk fibroin and silk‐inspired proteins are introduced as carrier materials by exploring recent advances to silk nanomedicine properties. The potential of bottom–up processing for silk nanoparticle production at a clinical scale is then explored.
Saphia A. L. Matthew, F. Philipp Seib
wiley   +1 more source

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