Results 211 to 220 of about 687,001 (274)

Sustainable alkane production from waste fatty acids via electrochemically coupled decarboxylation and hydrogenation. [PDF]

Nat Commun
Wei W, Wei Z, Luo X, Yuan H, Zhou Q, Ren X, Ouyang S, Zhang T, Ma D.   +8 more
europepmc   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Comprehensive Analysis of Sinomenii caulis and Menispermi rhizoma Based on Ultra-High Performance Liquid Chromatography and Ultra-High Performance Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometry. [PDF]

Anal Sci Adv
Tao Y, Zhang X, Li W, Wu Z, Duan S, Wan L, Li X, Zhang Y, Cheng X, Wei F.   +9 more
europepmc   +1 more source

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Electrochemical C4 alkylation of pyridine derivatives: Enhanced regioselectivity via silane assistance. [PDF]

Sci Adv
Yang Z, Liu X, Chen YX, Gao Y, Xiao X, Maekawa H, Zhang T, Hao XQ, Song MP.   +8 more
europepmc   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Enantioselective rapid assembly of bis-heterocycles by sequential palladium-catalyzed aza-Heck cyclization coupling reaction. [PDF]

Sci Adv
Wang L, Wu S, Zhang W, Zhang S, Dong J, Hu W, Zhou C, Gao L, Zhou L, Zhang J.   +9 more
europepmc   +1 more source

Sabatier‐Adjusted d‐Band Centers of Scalable Asymmetric Iron Sites toward Dynamic Nonradical Network for Fast Mineralization with Low‐Amount Oxidant

Advanced Science, EarlyView.
Asymmetric iron single‐atom catalysts with Sabatier‐adjusted d‐band centers overcome the inherent limitations of peroxymonosulfate (PMS) activation by establishing a synergistic nonradical pathway network, achieving exceptional pollutant mineralization (≈85%) at only one‐tenth conventional PMS dosage.
Yue Chen, Xunheng Jiang, Zhiyu Pan, Zhenjie Li, Chaohuang Chen, Can Li, Chenghui Luo, Shengkun Zhang, Daohui Lin, Xinhua Xu, Jiang Xu   +10 more
wiley   +1 more source

A 2nd-generation scalable synthesis of the HIV-1 entry inhibitor CJF-III-288 enabled by photoredox catalysis.

Chem Commun (Camb)
Nadraws JW, Pokle MS, Smith AB.
europepmc   +1 more source

Commentary on: Isolation and Quantification of Blood Apoptotic Bodies, a Non-invasive Tool to Evaluate Apoptosis in Patients with Ischemic Stroke and Neurodegenerative Diseases. [PDF]

Biol Proced Online
Soleymaninejadian E.
europepmc   +1 more source