Results 91 to 100 of about 3,048,513 (404)

Advances and Applications of Hybrid Graphene-Based Materials as Sorbents for Solid Phase Microextraction Techniques

Molecules
The advancement of traditional sample preparation techniques has brought about miniaturization systems designed to scale down conventional methods and advocate for environmentally friendly analytical approaches.
Alessandra Timóteo Cardoso, Rafael Oliveira Martins, Fernando Mauro Lanças   +2 more
doaj   +1 more source

Erratum to the paper: In vitro membrane binding and protein binding (IAM MB/PB technology) to estimate in vivo distribution: applications in early drug discovery

ADMET and DMPK, 2018
The authors of the original paper published with the same title: ADMET & DMPK 5(1) (2017) 14-38; doi: 10.5599/admet.5.1.373, apologize for the error in the plot on Figure 5. The erratum gives a correct plot.
Klara Livia Valko, Simon Teague, Charles Pudgeon   +2 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Direct analysis of hydrogen/deuterium mixtures: A concept [PDF]

, 1972
Fraction of deuterium/hydrogen mixture is isolated by column chromatography, ionized, and the HD+1-0 band absorption measured with conventional high-resolution infrared ...
Lord, H. C.
core   +1 more source

Switching the stereochemical outcome of 6-endo-trig cyclizations; Synthesis of 2,6-Cis-6-substituted 4-oxopipecolic acids [PDF]

, 2012
A base-mediated 6-endo-trig cyclization of readily accessible enone-derived α-amino acids has been developed for the direct synthesis of novel 2,6-cis-6- substituted-4-oxo-L-pipecolic acids. A range of aliphatic and aryl side chains were tolerated by
Agami C., Alastair A. Cant, Andrew Sutherland, Bernasconi R., Boger D. L., Cant A. A., Carbonnel S., Fowler L. S., Fowler L. S., Golubev A., Graham L. Simpson, Gutiérrez M. C., Hans Martin Senn, He M., Ireland R. E., Jatoi W. B., Johnson F., Jung J.-C., Kadouri-Puchot C., Lamarre D., Lindsay S. Fowler, Marin J., Mark Daly, Merino P., Occhiato E. G., Occhiato E. G., Purkayastha N., Purkayastha N., Romeo J. T., Romo D., Rudisill D. E., Schenk V. W., Smith A. B., Smith A. B., Smith A. B., Swindells D. C., Tanaka H., Vanderhaeghe H., Weigend F., Zacharius R. M., Zhao Y., Zhao Y.   +41 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Gas chromatography of volatile organic compounds [PDF]

, 1973
System has been used for problems such as analysis of volatile metabolities in human blood and urine, analysis of air pollutants, and in tobacco smoke chemistry.
Zlatkis, A.
core   +1 more source

ADVANCING THE SEPARATION SCIENCES THROUGH THE DELIVERY OF NEW MATERIALS, TECHNOLOGY AND METHODOLOGY. [PDF]

, 2013
A thesis and collection of works submitted to Plymouth University in partial fulfilment for the degree of DOCTOR OF ...
Paull, Brett
core   +2 more sources

Thin-Layer Chromatography.

Methods in molecular biology, 2021
G. Hölzl, Peter Dörmann
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source