Results 21 to 30 of about 10,732 (222)

Natural Chromenes and Chromene Derivatives as Potential Anti-trypanosomal Agents

Biological and Pharmaceutical Bulletin, 2008
The aim of the study was to investigate the anti-trypanocidal activities of natural chromene and chromene derivatives. Five chromenes were isolated from Piper gaudichaudianum and P. aduncum, and a further seven derivatives were prepared using standard reduction, methylation and acetylation procedures.
Batista Jr., João Marcos, Lopes, Adriana Aparecida, Ambrósio, Daniela Luz, Regasini, Luis Octávio, Kato, Massuo Jorge, Bolzani, Vanderlan da Silva, Cicarelli, Regina Maria Barreto, Furlan, Maysa   +7 more
openaire   +4 more sources

The crystal structures and Hirshfeld surface analysis of 6-(naphthalen-1-yl)-6a-nitro-6,6a,6b,7,9,11a-hexahydrospiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,11′-indeno[1,2-b]quinoxaline] and 6′-(naphthalen-1-yl)-6a′-nitro-6′,6a′,6b′,7′,8′,9′,10′,12a′-octahydro-2H-spiro[acenaphthylene-1,12′-chromeno[3,4-a]indolizin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compounds, 6-(naphthalen-1-yl)-6a-nitro-6,6a,6 b,7,9,11a-hexahydrospiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,11′-indeno[1,2-b]quinoxaline], C37H26N4O3S, (I), and 6′-(naphthalen-1-yl)-6a′-nitro-6′,6a′,6b′,7′,8′,9′,10′,12a′-octahydro-2H ...
G. Foize Ahmad, A. Syed Mohammed Mujaheer, M. NizamMohideen, M. Gulam Mohamed, V. Viswanathan   +4 more
doaj   +1 more source

Synthesis of chromeno[2,3-b]indeno[2,1-e]pyridine derivatives via K₂CO₃-promoted three-component reaction of 2-amino-4H-chromen-4-ones, aromatic aldehydes and 1H-Indene-1,3(2H)-dione

, 2023
An efficient process to access chromeno-fused azafluorenones (chromeno[2,3-b]indeno[2,1-e]pyridine) via the three-component reaction between 2-amino-4H-chromen-4-ones, aromatic aldehydes and 1H-indene-1,3(2H)-dione is described.
Chengjun Wu (389169), Wenyan Zhou (478857), Jianbo Gan (11015193), Cunde Wang (651658), Xinliang Shen (130631)   +4 more
core   +1 more source

The crystal structures of two new coumarin derivatives: 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compounds, 2-(4-{2-[(2-oxo-2H-chromen-4-yl)oxy]acetyl}piperazin-1-yl)acetamide, C17H19N3O5, (I), and N-(2,4-dimethoxybenzyl)-2-[(2-oxo-2H-chromen-4-yl)oxy]acetamide, C20H19NO6, (II), are new coumarin derivatives.
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, M. Govindhan, K. Subramanian   +4 more
doaj   +1 more source

Synthesis and Biological Evaluation of 2-(4,5,6,7-Tetrahydrobenzo[c]Isoxazol-3-yl)-4H-Chromen-4-Ones

, 2022
A new series of 2-(4,5,6,7-tetrahydrobenzo[c]isoxazol-3-yl)-4H-chromen-4-ones 5a-e were synthesized from 1-(2-hydroxyphenyl)-3-(4,5,6,7-tetrahydrobenzo[c]isoxazol-3-yl)propane-1,3-diones 4a-e in presence of acetic acid and conc. HCl.
Mubarak H. Shaikh (9373121), Bhausaheb K. Karale (9373115), Dipak N. Raut (13975629), Vijay M. Khedkar (554344), Hemantkumar N. Akolkar (9373106), Sadhana D. Mhaske (13975626), Sujata G. Dengale (9373109), Nirmala R. Darekar (9373118), Keshav K. Deshmukh (9373112)   +8 more
core   +1 more source

Crystal structure of 8-ethoxy-3-(4-nitrophenyl)-2H-chromen-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C17H13NO5, the coumarin ring system is essentially planar (r.m.s. deviation = 0.008 Å). The nitrophenyl ring makes a dihedral angle of 25.27 (9)° with the coumarin ring plane. The nitro group is almost coplanar with the phenyl ring
Shashikanth Walki, S. Naveen, S. Kenchanna, K. M. Mahadevan, M. N. Kumara, N. K. Lokanath   +5 more
doaj   +1 more source

The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

Molecules, 2011
New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5 ...
Abu Bakar Mohamad, Abdul Amir H. Kadhum, Ahmed A. Al-Amiery, Ahmed Y. Musa   +3 more
doaj   +1 more source

2-(2-Fluoro-[1,1′-biphenyl]-4-yl)-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide

Molbank, 2023
Herein, we report the synthesis of 2-(2-fluoro-[1,1′-biphenyl]-4-yl)-N-(4-methyl-2-oxo-2H-chromen-7-yl)propanamide in the reaction between 7-amino-4-methyl-2H-chromen-2-one and (±)-flurbiprofen. The newly-obtained bio-functional hybrid compound was fully
Stanimir Manolov, Iliyan Ivanov, Dimitar Bojilov, Paraskev Nedialkov   +3 more
doaj   +1 more source

Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
A series of new trimethoxyphenyl-4H-chromen derivatives as telomerase inhibitors through regulation dyskerin were designed and synthesised. The anticancer activity assay in vitro showed that compound 5i 3-(4-(4-isonicotinoylpiperazin-1-yl)butoxy)-5,7 ...
Jie Quan Wang, Meng Di Yang, Xing Chen, Yang Wang, Liu Zeng Chen, Xiu Cheng, Xin Hua Liu   +6 more
doaj   +1 more source

Prenylated flavonoids from maclura tinctoria fruits

Química Nova, 2013
A phytochemical investigation of Maclura tinctoria fruits yielded five flavonoids, including one prenylated flavonol (licoflavonol) and four prenylated isoflavones (wighteone, derrone, alpinum isoflavone, and 6-(2,2-dimethyl-2H-chromen-6-yl)-2-(1-hydroxy-
Sayuri de Oliveira Oyama, Luiz Antonio de Souza, Debora Cristina Baldoqui, Maria Helena Sarragiotto, Adriano Antônio Silva   +4 more
doaj   +1 more source