Results 31 to 40 of about 10,732 (222)

Michael condensation of 2-(4-carboxybenzylidene)-3,4-dihydronaphthalene-1(2H)-one with methylene active compounds in the targeted synthesis of O-heterocyclic hybrid systems [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия Химия. Биология. Экология, 2022
Approaches to the design of new hybrid polyoxaheterocyclic compounds based on the interaction of 2-(4-carboxybenzylidene)-3,4- dihydronaphthalene-1(2H)-one with methylene active compounds of the 2H-chromen-2-one series – 3 -(1,3-dioxobutan-1-yl)-2H-
Kanevskaya, Irina V.   +3 more
doaj   +1 more source

An Efficient Synthesis of Novel 3-[(Heteroaryl-2-ylimino)-methyl]-4-hydroxy-chromen-2-ones and Analogue of Tetrazole Derivatives and Their Antibacterial Activity

open access: yesMolbank, 2021
Synthesis of a series of the substituted [(pyridinyl and pyrimidin-2-ylimino)-ethyl]-4-hydroxy-chromen-2-ones and their tetrazole derivates is presented in this study. By catalytic condensation of 4-hydroxy-3-acetylcoumarine 2 and 2-aminopyridines 3(a-d),
Ramiz Hoti   +5 more
doaj   +1 more source

Design and Synthesis of Some Thiazolidin-4-ones Based on (7-Hydroxy-2-oxo-2H-chromen-4-yl) Acetic Acid

open access: yesMolecules, 2009
(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid methyl ester(1) upon reaction with ethyl bromoacetate furnishes (7-ethoxycarbonylmethoxy-2-oxo-2H-chromen-4-yl)-acetic acid methylester (2), which on treatment with 100% hydrazine hydrate yields (7 ...
Valentina Rajkovic   +4 more
doaj   +1 more source

Synthesis, structure elucidation, DNA-PK, PI3K, anti-platelet and anti-bacteria activity of linear 5, 6, and 10-substituted-2-morpholino-chromen-oxazine-dione and angular 3, 4, 6-substituted-8-morpholino-chromen-oxazine-2,10-dione

open access: yes, 2016
Coumarin, a naturally occurring or synthesised phytochemical, displays a wide range of biological activities. However, chromen-2-ones fused with 1,3-benzoxazine rings is not well documented and there is a gap in the literature which required engaging ...
Jasim M. A. Al-Rawi (2814616)   +1 more
core   +1 more source

One pot synthesis of substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-one derivatives [PDF]

open access: yes, 2017
The title compounds, substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-ones were obtained by reacting 3-aryl-1-(3-coumarinyl)propen-1-ones with 2-napthol catalyzed by DBU (1,8-diazabicyclo[5,4,0]undec-7-ene) and concentrated H2SO4 in ample yields.
Prasanna, Bethanamudi   +5 more
core   +1 more source

Polyphenol-Rich Duhuo Jisheng Decoction Enhances Mesenchymal Stem Cell-Derived Exosome-Mediated Chondroprotection via PI3K/AKT Signaling in Osteoarthritis. [PDF]

open access: yesFood Sci Nutr
This graphical abstract illustrates the chondroprotective mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) preconditioned with polyphenol‐rich Duhuo Jisheng Decoction (DHJST‐Exos). Enriched with bioactive compounds such as wogonin, quercetin, and kaempferol, DHJST‐Exos effectively ameliorate osteoarthritis (OA ...
Liao Z   +9 more
europepmc   +2 more sources

Isolation and Characterization of Two Coumarin Compounds from the Chloroform Fraction of Scadoxus multiflorus (Martyn) Raf. (Amaryllidaceae)

open access: yesChemistry Proceedings
In this study, the aerial parts of Scadoxus multiflorus were extracted using methanol through a maceration process. The resulting methanol crude extract was subsequently partitioned with solvents including n-hexane, chloroform, ethyl acetate, and n ...
Olaiya Akeem Ayodele   +3 more
doaj   +1 more source

A Novel Synthesis of 4H-Chromen-4-ones via Intramolecular Wittig Reaction

open access: yes, 2016
The acylphosphoranes formed in a sequential manner from the reaction of the silyl ester of O-acyl(aroyl)salicylic acids and (trimethylsilyl)methylenetriphenylphosphorane undergo intramolecular Wittig cyclization on the ester carbonyl to afford the 4H ...
Pradeep Kumar (310858)   +1 more
core   +1 more source

Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties

open access: yesMolecules, 2018
A series of 2-imino-2H-chromen-3-yl-1,3,5-triazine compounds 5–12, which are namely hybrids of 2,4-diamino-1,3,5-triazines and 2-imino-coumarins, was synthesized by reacting 2-(4,6-diamine-1,3,5-triazin-2-yl)acetonitriles 1–4 with 2 ...
Anna Makowska   +4 more
doaj   +1 more source

Novel multicomponent synthesis of 2-OXO-1, 2-diphenylethylidene hydrazinyl thiadiazinyl-2H-chromen-2-one derivatives

open access: yes, 2016
A series of novel 2-oxo-1,2-diphenylethylidene hydrazinyl thiadiazinyl-2H-chromen-2-ones (shown in Scheme 1) have been synthesized via multicomponent approach by the reaction of equimolar amount of benzil (1), thiocarobohydrazide (2), and substituted of
Krishnaiah Vaarla (2887484)   +2 more
core   +1 more source

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