Results 51 to 60 of about 10,732 (222)

Antifungal activity of a novel chromene dimer [PDF]

Journal of Industrial Microbiology & Biotechnology, 2007
The activity on Aspergillus spp. growth and on ochratoxin A production of two novel chromene dimers (3) was evaluated. The results of the bioassays indicate that the chromene dimer 3a inhibited mycelia growth by approximately 50% (EC(50)) at 140.1 micromol L(-1) for A. niger, 384.2 micromol L(-1) for A. carbonarius, 69.1 micromol L(-1) for A. alliaceus
Abrunhosa, Luís, Costa, M., Areias, F., Venâncio, Armando, Proença, M. Fernanda R. P.   +4 more
openaire   +3 more sources

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Synthesis of Pyrano[2,3-f]chromen-2-ones vs. Pyrano[3,2-g]chromen-2-ones through Site Controlled Gold-Catalyzed Annulations.

, 2019
Regioselective access to 10-substituted-2H,8H-pyrano[2,3-f]chromen-2-ones through the gold-catalyzed intramolecular hydroarylation of readily available 7-(prop-2-yn-1-yloxy)-2H-chromen-2-one derivatives at their C-8 congested position was investigated by
Giancarlo Fabrizi, Francesca Ghirga, Antonella Goggiamani and Antonia Iazzetti, Andrea Fochetti, Antonio Arcadi, Alessia Ciogli, Roberta Franzini   +6 more
core   +2 more sources

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Phytochemical Constituents of F. Sagittifolia Warburg ex Mildbraed & Burret Leaves with Antimicrobial Activity

Biology, Medicine & Natural Product Chemistry, 2022
The leaves and bark of Ficus sagittifolia have been used as a cure for stomach and pulmonary disorders, respectively. The bark is edible and is taken against colic. From the leaves of F. sagittifolia, a steroidal glycoside named Stigmast-5,22-diene-3-O-β-
Olayombo Margaret Taiwo, Olaoluwa Omosalewa Olaoluwa, Olapeju Oluyemisi Aiyelaagbe, Josphat Clement Matasyoh   +3 more
doaj   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Crystal structure of the triethylammonium salt of 3-[(4-hydroxy-3-methoxyphenyl)(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2-oxo-2H-chromen-4-olate

Acta Crystallographica Section E: Crystallographic Communications, 2018
The reaction between 3,3′-[(3-methoxy-4-hydroxyphenyl)methanediyl]bis(4-hydroxy-2H-chromen-2-one) and triethylamine in methanol yielded the title compound triethylammonium 3-[(4-hydroxy-3-methoxyphenyl)(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2-oxo-2H ...
Muhammad Ikram, Sadia Rehman, Afzal Khan, Carola Schulzke   +3 more
doaj   +1 more source

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

Plant, Cell &Environment, EarlyView.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros, Asier Largo‐Gosens, Cristina Úbeda, Cristina Hernández‐Fernández, Alba Manga‐Robles, Diego Rebaque, Antonio Encina, Hugo Mélida   +7 more
wiley   +1 more source

Synthesis of novel 3-[(2R*)-2-[(2S*)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]-urea/thiourea derivatives and evaluation of their antimicrobial activities

, 2019
A new series of biologically active 3-[(2R*)-2-[(2S*)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]-urea/thiourea derivatives (1) have been designed and synthesized in four steps from 6-fluoro-3,4-dihydro-2-(oxiran-2-yl)-2H-chromene (2).
Srimurugan S. (6925043), Madhava Rao Mannam (6394613), Prasad K. R. S. (6925046), Pramod Kumar (2102215), Naga Raju Chamarthi (3916643)   +4 more
core   +1 more source