Results 61 to 70 of about 10,732 (222)
Ni(II) and Zn(II) complexes were synthesized from tridentate 3-formyl chromone Schiff bases such as 3-((2-hydroxyphenylimino)methyl)-4H-chromen-4-one (HL1), 2-((4-oxo-4H-chromen-3-yl)methylneamino)benzoic acid (HL2), 3-((3-hydroxypyridin-2-ylimino)methyl)
Palakuri Kavitha, K. Laxma Reddy
doaj +1 more source
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
Chemoenzymatic synthesis of both enantiomers of 3-hydroxy-2,3-dihydro-4H-chromen-4-one
4-Oxo-3,4-dihydro-2-chromen-3-yl acetate is synthesized using manganese(III)acetate starting from 2,3-dihydro-4H-chromen-4-one. K2CO3 mediated hydrolysis of 4-oxo-3,4-dihdro-2-chromen-3-yl acetate furnished 3-hydroxy-2,3-dihydro-4H-chromen-4-one in high ...
Sesenoglu, O +4 more
core +1 more source
Revised Structure by Computational Methods for a Coumarin Isolated from (Rutaceae)
On the basis of theoretical methods using DFT/B3LYP/6-31G * geometries and HF/6-311+G** GIAO NMR predictions, the 13 C NMR spectroscopic data of a coumarin from Zanthoxylum rhoifolium was reassigned.
Augusto Rivera, Jaime Rios-Motta
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Tectorigenin monohydrate: an isoflavone from Belamcanda chinensis
The title compound [systematic name: 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one monohydrate], C16H12O6·H2O, is isolated from Belamcanda chinensis and is said to have antimicrobiotic and anti-inflammatory effects. The chromen-4-one
Benguo Liu +3 more
doaj +1 more source
The selective nature through which coumarin compounds produced by different species of plants target PQS signalling in Pseudomonas aeruginosa and select for distinct phenotypic responses in key pathogenic organisms adds to the growing evidence of their utility as natural virulence suppressors. ABSTRACT Cell‐to‐cell communication in microbial systems is
Dylan Boon +8 more
wiley +1 more source
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang +8 more
wiley +1 more source
A solvent-controlled reaction of 3,3a-dihydro-9H-furo[3,4-b]chromen-9-one with malononitrile to access 3-(tetrahydrofuran-2-yl)-4H-chromen-4-one is described.
Hong-Yan Huang +5 more
core +1 more source
New coumarin derivatives, namely (2-(4-methyl-2-oxo-<em>2H</em>-chromen-7-yloxy)-<em>N</em>-(4-oxo-2-phenylthiazolidin-3-yl)acetamide, <em>N</em>-(2-(3-methoxyphenyl)-4-oxothiazolidin-3-yl)-2-(4-methyl-2-oxo-<em> ...
Alary Fabienne +3 more
doaj +1 more source
Uroporphyrinogen decarboxylase as a potential target for specific components of traditional Chinese medicine: a virtual screening and molecular dynamics study. [PDF]
Uroporphyrinogen decarboxylase (UROD) has been suggested as a protectant against radiation for head and neck cancer (HNC). In this study, we employed traditional Chinese medicine (TCM) compounds from TCM Database@Taiwan (http://tcm.cmu.edu.tw/) to screen
Yung-An Tsou +4 more
doaj +1 more source

