Results 81 to 90 of about 10,732 (222)

Modulation of miR‐204 and miR‐375 Expression by Flavonoid Chrysin Treatment During Melphalan‐Induced Histopathological Damage in Adult Rat Skin and Hair Tissue

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Rats were treated with melphalan (1.5 mg/kg) with or without chrysin (50 or 75 mg/kg) for 21 days. Melphalan reduced epidermal thickness, disrupted the hair follicle cycle, increased apoptosis, suppressed autophagy, and upregulated miR‐204/miR‐375.
Maryam Moghimian, Zahra Parsamanesh, Zahra Rajabzadeh, Negar Shafaei‐Bajestani, Malihe Soltani   +4 more
wiley   +1 more source

Correction: Unprecedented formation of 3-(tetrahydrofuran-2-yl)-4H-chromen-4-one in a reaction between 3,3a-dihydro-9H-furo[3,4-b]chromen-9-one and malononitrile

, 2017
Correction for ‘Unprecedented formation of 3-(tetrahydrofuran-2-yl)-4H-chromen-4-one in a reaction between 3,3a-dihydro-9H-furo[3,4-b]chromen-9-one and malononitrile’ by Jie-Jie Liu, et al., Org. Biomol. Chem., 2017, DOI: 10.1039/c7ob00904f.
Hong-Yan Huang, Li Liu, Dong Wang, Liang Cheng, Feng Wei, Jie-Jie Liu   +5 more
core   +1 more source

Syntheses of Benzo[]Chromen-6-ones by Palladium Catalyzed C–H Bond Activation using Diazonium Salts

Natural Product Communications, 2017
An efficient palladium catalyzed C-H bond activation for the synthesis of benzo[ c ]chromen-6-ones using diazonium salts is described. In the presence of Pd(OAc) 2 , dppp, PivOH and K 2 CO 3 , the diazonium salt can be transformed into the product ...
Liang-Zhu Huang, Rui-Yue Ma, Lu-Nan Zhou, Zhen-Ting Du, Tao Zhang   +4 more
doaj   +1 more source

The regulation mechanism of the excited-state behaviour of 3-Hydroxy-2-(1-ethyl-1H-pyrazol-3-yl)-4H-chromen-4-one fluorophore by solvent polarity: a computational study

, 2022
Given the unique spectral properties of exhibiting dual-band fluorescence, excited-state intramolecular proton transfer (ESIPT) materials have attracted wide attention.
Wenpeng Yang (283124), Yanshan Tian (12454836), Dapeng Yang (484094), Rui Zheng (313520)   +3 more
core   +1 more source

3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one inhibits allergic reactions in IgE-mediated RBL-2H3 cells and a passive cutaneous anaphylaxis mouse model

Applied Biological Chemistry
Allergic reactions occur when the immune system overreacts to generally harmless substances, leading to both acute and chronic diseases, which can be fatal.
Moonsu Kim, Huiji Kim, Sun Young Moon, Seong-Ah Shin, Minji Kim, Seyeon Choi, Sugeun Gwon, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee   +9 more
doaj   +1 more source

Mean absolute errors computed for selected bond lengths (Ao) and angles (degree) of the selected potential target compounds (V-IX) of Coumarin derivative verses 3-((2-Oxo-2H-chromen-3-yl)carbonyl)pyridinium hydrogen squarate calculated at long-range corrections wb97xd/6-311++g(d,p) level of theory. The X-ray crystal structure data (CCDC: 697425).

Mean absolute errors computed for selected bond lengths (Ao) and angles (degree) of the selected potential target compounds (V-IX) of Coumarin derivative verses 3-((2-Oxo-2H-chromen-3-yl)carbonyl)pyridinium hydrogen squarate calculated at long-range ...
Hadia Almahli (8099222), Mohamed Farouk Hamissa (18127425), Eslam B. Elkaeed (9952518), Mahmoud A. El Hassab (9952515), Mahmoud A. Noamaan (18127422), Ahmed Sabt (5450795), Abdalkareem Nael Maslamani (18127428), Moataz A. Shaldam (12429873), Wagdy M. Eldehna (4260952), Taghreed A. Majrashi (5991263)   +9 more
core   +1 more source

Unravelling the therapeutic effect of naturally occurring Bauhinia flavonoids against breast cancer: an integrated computational approach

Open Chemistry
Breast cancer is among the cancers contributing to the drastic reduction in the life expectancy of women worldwide. Naturally occurring flavonoids have been identified as one of the primary therapeutic agents in medicinal plants.
Faloye Kolade O., Tripathi Manish K., Fakola Emmanuel G., Bankole Regina B., Obaidullah Ahmad J., Alotaibi Jawaher M., Olusola Ayobami J., Ogundele Seun B., Olajubutu Oluwabukumi G., Omoyeni Olajide B., Mponda John   +10 more
doaj   +1 more source

Synthesis of 2-(1,2,4-oxadiazol-5-yl)-2,3-dihydro-4H-chromen-4-ones

, 2020
Simple and efficient synthesis of 2-(1,2,4-oxadiazol-5-yl)-2,3-dihydro-4H-chromen-4-ones is elaborated. The method relies on CDI-mediated cyclocondensation of substituted 4-oxochromane-2-carboxylic acids and amidoximes.
Kysil, Andrii, Bugera, Oleksandra, Voitenko, Zoia, Yegorova, Tetyana, Biitseva, Angelina   +4 more
core   +1 more source

Natural phenolic compounds from Satureja L. as inhibitors of COVID-19 protease (Mpro): Computational investigations

International Journal of Plant Based Pharmaceuticals, 2022
Coronavirus (SARS-CoV-2) causes a new type of severe acute respiratory syndrome that first appeared in Wuhan in December 2019; it is a very fast-spreading and deadly virus. Therefore, urgent discovery or development of “lead compounds” against this virus
Faika Başoğlu-Ünal, Selin Tufan, Nur Tan   +2 more
doaj  

Synthesis and Antioxidant Activity of Some New Coumarinyl-1,3-Thiazolidine-4-ones

Molecules, 2010
A series of Schiff’s bases (E)-N-2-aryliden-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetohydrazides 2a-l and N-(2-(substituted phenyl)-4-oxo-thiazolidin-3-yl)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetamides 3a-l were synthesized and evaluated for their ...
Valentina Rajković, Bojan Šarkanj, Elizabeta Has-Schön, Milan Čačić, Maja Molnar   +4 more
doaj   +1 more source