Results 21 to 30 of about 1,409 (124)
Rare Presentation of Kaposi Sarcoma Mimicking Madura Foot: A Case Report
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Kaposi sarcoma (KS) is a low‐grade angioproliferative tumor primarily associated with HIV but also seen in immunocompetent individuals. Its presentation can mimic infectious diseases such as Madura foot (mycetoma), a chronic granulomatous infection endemic to tropical regions.
Jeminah Nyeenya Nakatudde +2 more
wiley +1 more source
Small Science, Volume 5, Issue 8, August 2025.This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia +9 more
wiley +1 more source
Top 10 Public Health Challenges for 2024: Charting a New Direction for Global Health Security
Public Health Challenges, Volume 4, Issue 1, March 2025.The top 10 public health challenges for 2024 emphasize the need for a unified global approach to address infectious diseases, health disparities, climate change, mental health, substance use, reproductive health, food safety, emerging technologies, healthcare costs, and global collaboration.
Don Eliseo Lucero‐Prisno III +30 more
wiley +1 more source
Clinical Presentation and Histopathological Characteristics of Sporotrichosis
Journal of Cosmetic Dermatology, Volume 24, Issue 3, March 2025.ABSTRACT Objective Sporotrichosis is the most prevalent deep mycosis worldwide. The differential diagnosis of its clinical symptoms and histopathological features presents considerable complexity. A thorough understanding of the clinical manifestations and pathological characteristics of sporotrichosis is crucial for its accurate clinical diagnosis ...
Xiaohong Zhao, Panpan Li, Jianxun Yang
wiley +1 more source
Enhancing Flucytosine Anticandidal Activity Using PEGylated Squalene Nanocarrier
ChemMedChem, Volume 20, Issue 1, January 2, 2025.Our study focused on improving the effectiveness of the antifungal drug 5‐fluorocytosine (5FC) by loading it in micellar structures formed by PEGylated squalene copolymer. The obtained results for 5FC‐loaded micelles showed in vitro prolonged release under physiological conditions and improved in vitro antifungal activity without cytotoxicity for ...
Bogdan‐Florin Craciun +3 more
wiley +1 more source
Health Science Reports, Volume 7, Issue 11, November 2024.ABSTRACT Background and Aim Leprosy is one of the most common skin neglected tropical diseases in Ethiopia posing social stigma, physical disability, deformity, discrimination, loss of social status, and poor quality of life in families. Hence, evidence‐based collaborative inter‐sectoral actions should be performed to reduce and eliminate its burden in
Alemu Gedefie +11 more
wiley +1 more source
An unusual presentation of extragenital lichen sclerosus—An extensive keratotic variant
Skin Health and Disease, Volume 4, Issue 3, June 2024.We outline a case of a 71‐year‐old woman who presented a keratotic and atrophic warty‐like plaques on her lower limbs, which limited the movements in her right lower extremity. A skin radial biopsy of one the plaques was performed and the diagnosis of extragenital lichen sclerosus was established. The patient in this case showed an unusual variant with
Mario Magaña +1 more
wiley +1 more source
Skin innate immune response against fungal infections and the potential role of trained immunity
Mycoses, Volume 67, Issue 1, January 2024.Abstract Fungal skin infections are distributed worldwide and can be associated with economic and social traits. The immune response related to skin cells is complex and its understanding is essential to the comprehension of each cell's role and the discovery of treatment alternatives. The first studies of trained immunity (TI) described the ability of
Amanda Bombassaro +7 more
wiley +1 more source
Journal of Tropical Medicine, Volume 2024, Issue 1, 2024.Background. Neglected tropical diseases (NTDs) are a heterogeneous group of medical conditions that commonly occur in underprivileged populations. NTDs are primarily diagnosed in tropical areas. Although South Africa is not situated in a tropical region, the high poverty rate makes the country susceptible to some NTDs. Limited data are available on the
Danita Linda le Grange +5 more
wiley +1 more source