Results 211 to 220 of about 39,719 (247)
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Plasma Chromogranin-A in Primary Hyperparathyroidism*
The Journal of Clinical Endocrinology & Metabolism, 1989We sought an explanation for prior findings of high plasma chromogranin-A (Chr-A) in primary hyperparathyroidism. Chr-A was measured in plasma samples from 55 controls and 73 patients with primary hyperparathyroidism caused by adenoma (n = 14), sporadic or familial hyperplasia (n = 10), or familial multiple endocrine neoplasia type 1 (FMEN1; n = 49 ...
M S, Nanes, D T, O'Connor, S J, Marx
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Chromogranin A assay in clinical practice
Annales d'Endocrinologie, 2010Chromogranins belong to the family of secretory chromogranin and secretogranin proteins. They are found in secretory vesicles throughout the neuroendocrine system. Chromogranin A (CgA) is the main component. CgA acts as a prohormone submitted to processes of degradation through which active peptides are generated.
M, d'Herbomez +4 more
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WE‐14, a Chromogranin A‐Derived Neuropeptide
Annals of the New York Academy of Sciences, 2002Abstract: The neuropeptide WE‐14 is derived from the posttranslational processing of chromogranin A (CgA). While CgA is expressed in a preponderance of neuroendocrine cells, WE‐14 is generated in a distinct subpopulation of CgA‐immunopositive cells, most notably in the adrenal, pituitary, and parathyroid glands.
Curry, William +7 more
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Increased Fecal Levels of Chromogranin A, Chromogranin B, and Secretoneurin in Collagenous Colitis
Inflammation, 2013Interactions between the enteric nervous system and the immune system are suggested to play an important role in the pathophysiology of inflammatory bowel disease (IBD). This study aims to determine if chromogranin A (CgA), chromogranin B (CgB), and secretoneurin (SN) are detectable in feces (F) from patients with collagenous colitis (CC) and to ...
Michael, Wagner +5 more
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Chromogranin A and the Tumor Microenvironment
Cellular and Molecular Neurobiology, 2010Chromogranin A (CgA) is an acidic glycoprotein belonging to a family of regulated secretory proteins stored in the dense core granules of the adrenal medulla and of many other neuroendocrine cells and neurons. This protein is frequently used as a diagnostic and prognostic serum marker for a range of neuroendocrine tumors.
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Chromogranin A in Human Hypertension
Hypertension, 1995AbstractMultiple heritable traits are associated with essential (genetic) hypertension in humans. Because chromogranin A is increased in both human and rodent genetic hypertension, we examined the influence of heredity and blood pressure on chromogranin A in humans.
Marwan A. Takiyyuddin +10 more
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Chromogranin a as a Biomarker in Cardiovascular Disease
Biomarkers in Medicine, 2013Chromogranin A is known as an important marker of neuroendocrine tumors. In cardiovascular medicine, however, chromogranin A measurement has only recently gained interest, since increased concentrations in the circulation are associated with risk of clinical worsening and death in patients with acute coronary syndromes or chronic heart failure. In this
Goetze, Jens P +3 more
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Chromogranin A expression in human colonic adenocarcinoma.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia, 2002The presence of CgA positive cells occuring in scattered elements or in clusters within human colonic adenocarcinomas has been documented in recent data. The number of these cases has ranged from 10% to 40% depending on the method of demonstration. The aim of this study is to assess the presence of CgA positive cells on a set of 60 tumours that, by ...
ROMEO R +3 more
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The Chromogranin–Secretogranin Family
New England Journal of Medicine, 2003Laurent Taupenot, Daniel T O'connor
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