Results 191 to 200 of about 30,456 (242)

Chromogranin A and Chromogranin B in Noninvasive and Invasive Breast Carcinoma

Endocrine Pathology, 2002
Recent progress in the study of chromogranins has revealed that there are many novel peptides derived from chromogranin with their multiple pathophysiologic roles. To learn the possible roles of chromogranin in breast carcinoma, we immunohistochemically investigated tissue localization of chromogranin A (CgA) and chromogranin B (CgB) in 10 normal ...
Noriko, Kimura, Ryuichi, Yoshida, Shin-ichiro, Shiraishi, Monika, Pilichowska, Noriaki, Ohuchi   +4 more
openaire   +2 more sources

Measurements of chromogranin B can serve as a complement to chromogranin A

Regulatory Peptides, 2007
CgA has been shown to be an excellent marker for neuroendocrine tumours. However, there are two major drawbacks with CgA measurements; elevated levels are common in patients with decreased renal function and in patients on treatment with proton pump inhibitors. These problems are not seen with CgB measurements.
Mats, Stridsberg, Barbro, Eriksson, Bengt, Fellström, Gudjon, Kristiansson, Eva, Tiensuu Janson   +4 more
openaire   +2 more sources

Increased Fecal Levels of Chromogranin A, Chromogranin B, and Secretoneurin in Collagenous Colitis

Inflammation, 2013
Interactions between the enteric nervous system and the immune system are suggested to play an important role in the pathophysiology of inflammatory bowel disease (IBD). This study aims to determine if chromogranin A (CgA), chromogranin B (CgB), and secretoneurin (SN) are detectable in feces (F) from patients with collagenous colitis (CC) and to ...
Michael, Wagner, Mats, Stridsberg, Christer G B, Peterson, Per, Sangfelt, Maria, Lampinen, Marie, Carlson   +5 more
openaire   +2 more sources

Chromogranin-B regulation of IAPP and insulin secretion

Regulatory Peptides, 2000
In the endocrine pancreas, chromogranin-A and pancreastatin have been suggested to inhibit islet insulin secretion, whereas chromogranin-B has not been studied in this context. Furthermore, a putative effect by chromogranins on IAPP secretion is unknown.
E, Karlsson, M, Stridsberg, S, Sandler
openaire   +2 more sources

Chromogranin A, chromogranin B and secretogranin II mRNAs in the pituitary and adrenal glands of various mammals. Regulation of chromogranin A, chromogranin B and secretogranin II mRNA levels by estrogen.

Laboratory investigation; a journal of technical methods and pathology, 1992
The chromogranin/secretogranin (Cg/Sg) acidic proteins are widely distributed in vertebrate species. They are thought to play a role in hormone packaging within secretory granules, in hormone secretion, and serve as prohormones for various proteolytic cleavage products.
R V, Lloyd, K, Hawkins, L, Jin, E, Kulig, K, Fields   +4 more
openaire   +2 more sources

Regulation of Chromogranin A and Chromogranin B (Secretogranin I) Synthesis in Bovine Cultured Chromaffin Cells

Journal of Neuroendocrinology, 1991
AbstractIn the present study we investigated the regulation of Chromogranin A (CGA) and Chromogranin B (CGB) biosynthesis in bovine chromaffin cells maintained in primary culture. Cellular proteins were labelled with [35S]methionine and the incorporated radioactivity was used as an index of the synthesis rate.
E, Galindo, M F, Bader, D, Aunis
openaire   +2 more sources

Regulation of circulating chromogranin B levels in heart failure

Biomarkers, 2017
Chromogranin B (CGB) regulates B-type natriuretic peptide (BNP) production. Circulating CGB levels are elevated in heart failure (HF) animal models and HF patients, but also increase in healthy individuals in response to physical activity. Therefore, CGB seems to integrate information from myocardial stress and systemic neuro-endocrine activation ...
Felix M. Heidrich, Carolin Melz, Mimi S. Buechau, Christian Pfluecke, Silvio Quick, Uwe Speiser, David M. Poitz, Antje Augstein, Tobias Ruf, Nadine K. Wässnig, Akram Youssef, Ruth H. Strasser, Stephan Wiedemann   +12 more
openaire   +2 more sources

Interaction of calcium with porcine adrenal chromogranin A (secretory protein-I) and chromogranin B (secretogranin I)

American Journal of Physiology-Endocrinology and Metabolism, 1989
Secretory granules of endocrine cells contain one or more of the acidic secretory proteins chromogranin A (secretory protein-I), chromogranin B (secretogranin I), and secretogranin II (chromogranin C). It has been proposed that these proteins play a role in the packaging of secretory products.
S U, Gorr, J, Shioi, D V, Cohn
openaire   +2 more sources

Sex‐Related Differences in Chromogranin A, Chromogranin B and Secretogranin II Gene Expression in Rat Pituitary

Journal of Neuroendocrinology, 1992
AbstractChromogranin A, an acidic secretory protein, is widely distributed throughout diverse endocrine cells and the central and peripheral nervous systems. Chromogranin A is co‐stored and co‐secreted from secretory vesicles together with the endogenous hormones or neurotransmitters.
R, Fischer-Colbrie, K W, Schmid, S K, Mahata, M, Mahata, A, Laslop, J W, Bauer   +5 more
openaire   +2 more sources

Differential regulation of chromogranin A, chromogranin B and secretogranin II in rat brain by phencyclidine treatment

Neuroscience, 2001
Chromogranin A, chromogranin B and secretogranin II belong to the chromogranin family which consists of large protein molecules that are found in large dense core vesicles. Chromogranins are endoproteolytically processed to smaller peptides. This study was designed to elucidate the regulation of chromgranin expression by acute and subchronic ...
J, Marksteiner, U, Weiss, C, Weis, A, Laslop, R, Fischer-Colbrie, C, Humpel, J, Feldon, W W, Fleischhacker   +7 more
openaire   +2 more sources