Results 71 to 80 of about 30,656 (238)

Glucagonoma-associated dilated cardiomyopathy refractory to somatostatin analogue therapy

Endocrinology, Diabetes & Metabolism Case Reports, 2019
A 67-year-old woman presented with a generalised rash associated with weight loss and resting tachycardia. She had a recent diagnosis of diabetes mellitus. Biochemical evaluation revealed elevated levels of circulating glucagon and chromogranin B.
Michal Barabas, Isabel Huang-Doran, Debbie Pitfield, Hazel Philips, Manoj Goonewardene, Ruth T Casey, Benjamin G Challis   +6 more
doaj   +1 more source

Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon, Laura M. Warmke, Ahmed K. Alomari, Rachel P. Kowal   +3 more
wiley   +1 more source

Long-Term Survival in a Dog After Adrenalectomy and Splenectomy for Two Different Malignancies with Portal Vein Involvement

Animals
Concurrent occurrence of two independent primary malignancies in a single dog is rare and presents diagnostic and surgical challenges. A 9-year-old neutered male Cocker Spaniel was diagnosed with adrenal pheochromocytoma and splenic diffuse large B-cell ...
Seung-Hyun Kim, Jun-Gyu Park, Jang-Han Yoon, Yeong-Bin Baek, Sang-Ik Park   +4 more
doaj   +1 more source

Biomarcadores no líquido cefalorraquidiano para o diagnóstico precoce de doença de Parkinson.

Acta Médica Portuguesa, 2011
In current medical practice, the diagnosis of Parkinson's disease remains essentially clinical. This practice determines that the diagnosis of Parkinson's disease is done in an already advanced neuropathological stage of the disease.
Andreia Gomes da Costa, Miguel Fernandes Gago, Carolina Garrett   +2 more
doaj   +1 more source

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]

, 2018
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto, Campana, Davide, Di Giacinto, Paola, Isidori, Andrea, Lania, Andrea, Lenzi, Andrea, Rizza, Laura, Rota, Francesca, Zuppi, Paolo   +8 more
core   +1 more source

Cervical Small Cell Neuroendocrine Carcinoma Initially Detected on Cytology: Diagnostic Pitfalls and Clues

Cytopathology, EarlyView.
This case describes the initial detection of cervical small cell neuroendocrine carcinoma on conventional endometrial and cervicovaginal liquid‐based cytology. Given its rarity and high aggressiveness, early recognition and rapid, intensive treatment are crucial for improving patient outcomes.
Yesul Jeong
wiley   +1 more source

Small peptide CSF fingerprint of amyotrophic lateral sclerosis.

PLoS ONE
BackgroundAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by abnormal protein aggregation in the motor neurons. Present and earlier proteomic studies to characterize peptides in cerebrospinal fluid (CSF) associated with ...
Rea Lumi, Susanne Petri, Justyna Siwy, Agnieszka Latosinska, Julia Raad, Petra Zürbig, Thomas Skripuletz, Harald Mischak, Joachim Beige   +8 more
doaj   +1 more source

Chromogranin A in neurons of the rat cerebellum and spinal cord: quantification and sites of expression [PDF]

, 1992
Chromogranin A (CGA) is an abundant protein of dense-cored secretory vesicles in endocrine and neuronal cells. The present study, for the first time, compares CGA of neurons of the central nervous system with the CGA of adrenal origin.
Bergmann, M., Gratzl, Manfred, Lahr, G., Mayerhofer, Artur, Takiyyuddin, M. A.   +4 more
core   +1 more source

When Small Cells Matter: Diagnosing Bladder Small Cell Carcinoma on Urine Cytology

Cytopathology, EarlyView.
Small cell carcinoma of the bladder is rare, aggressive and diagnostically challenging on urine cytology. We report a case detected in urine and confirmed by cell block immunohistochemistry, highlighting the importance of careful assessment and limitations of the Paris System.
Haley Corbin, Samer Khader, Gabriela Quiroga‐Garza, Liron Pantanowitz   +3 more
wiley   +1 more source

Exploring Chromogranin A (CgA) as a Diagnostic Marker in Hypothermia-Related Deaths: Two Case Studies and a Literature Review

Diagnostics
Background: Hypothermia, occurring when core temperature drops below 35 °C, can lead to death when the body’s heat loss exceeds its heat production. This study investigates two hypothermia-related deaths, exploring the utility of immunohistochemistry ...
Luca Tomassini, Erika Buratti, Giulia Ricchezze, Roberto Scendoni   +3 more
doaj   +1 more source