Results 1 to 10 of about 2,220 (203)

Chromogranin A and Its Fragments in the Critically Ill: An Expanding Domain of Interest for Better Care [PDF]

Pharmaceutics, 2022
Life-threatening diseases challenge immunity with a release of chromogranins. This report focuses on Chromogranin A (CGA) and some of its derived peptides in critically ill patients, with attention paid to their potential to become biomarkers of severity
Francis Schneider, Raphaël Clère-Jehl, Francesco Scavello, Thierry Lavigne, Angelo Corti, Tommaso Angelone, Youssef Haïkel, Philippe Lavalle   +7 more
doaj   +2 more sources

The antimicrobial peptides secreted by the chromaffin cells of the adrenal medulla link the neuroendocrine and immune systems: From basic to clinical studies [PDF]

Frontiers in Immunology, 2022
The increasing resistance to antibiotic treatments highlights the need for the development of new antimicrobial agents. Antimicrobial peptides (AMPs) have been studied to be used in clinical settings for the treatment of infections.
Francesco Scavello, Francesco Scavello, Naji Kharouf, Naji Kharouf, Philippe Lavalle, Youssef Haikel, Youssef Haikel, Francis Schneider, Francis Schneider, Marie-Hélène Metz-Boutigue   +9 more
doaj   +2 more sources

Evidence for the existence of secretory granule (dense-core vesicle)-based inositol 1,4,5-trisphosphate-dependent Ca2+ signaling system in astrocytes. [PDF]

PLoS ONE, 2010
BACKGROUND: The gliotransmitters released from astrocytes are deemed to play key roles in the glial cell-neuron communication for normal function of the brain. The gliotransmitters, such as glutamate, ATP, D-serine, neuropeptide Y, are stored in vesicles
Yong Suk Hur, Ki Deok Kim, Sun Ha Paek, Seung Hyun Yoo   +3 more
doaj   +1 more source

Cateslytin, a chromogranin A derived peptide is active against Staphylococcus aureus and resistant to degradation by its proteases. [PDF]

PLoS ONE, 2013
Innate immunity involving antimicrobial peptides represents an integrated and highly effective system of molecular and cellular mechanisms that protects host against infections. One of the most frequent hospital-acquired pathogens, Staphylococcus aureus,
Rizwan Aslam, Céline Marban, Christian Corazzol, François Jehl, François Delalande, Alain Van Dorsselaer, Gilles Prévost, Youssef Haïkel, Corinne Taddei, Francis Schneider, Marie-Hélène Metz-Boutigue   +10 more
doaj   +1 more source

Assessment of stress response attenuation with caudal morphine using a surrogate marker during pediatric cardiac surgery

Annals of Cardiac Anaesthesia, 2022
Background: Measurement of biomarkers representing sympathetic tone and the surgical stress response are helpful for objective comparison of anesthetic protocols.
Madan Mohan Maddali, Fathiya Al Shamsi, Nishant Ram Arora, Ramachandhiran Venkatachlam, Panchatcharam Murthi Sathiya   +4 more
doaj   +1 more source

A novel stepwise integrative analysis pipeline reveals distinct microbiota-host interactions and link to symptoms in irritable bowel syndrome

Scientific Reports, 2021
Although incompletely understood, microbiota-host interactions are assumed to be altered in irritable bowel syndrome (IBS). We, therefore, aimed to develop a novel analysis pipeline tailored for the integrative analysis of microbiota-host interactions ...
Annikka Polster, Lena Öhman, Julien Tap, Muriel Derrien, Boris Le Nevé, Johanna Sundin, Hans Törnblom, Marija Cvijovic, Magnus Simrén   +8 more
doaj   +1 more source

Immunological characterization of chromogranins A and B and secretogranin II in the bovine pancreatic islet [PDF]

, 1987
Antisera against chromogranin A and B and secretogranin II were used for analysing the bovine pancreas by immunoblotting and immunohistochemistry. All three antigens were found in extracts of fetal pancreas by one dimensional immunoblotting. A comparison
A Iacangelo, AD Smith, BS Wilson, C Hagn, D Grube, D Grube, D Grube, DT O'Connor, DT O'Connor, DV Cohn, E El-Nady, FU Reiffen, FU Reiffen, G Falkensammer, G Falkensammer, G Rindi, H Blaschko, H Lassmann, H Winkler, HD Mayor, IM Varndell, JA Nolan, JC Hutton, K Tatemoto, KB Helle, KB Helle, L Kilpatrick, LA Sternberger, LE Eiden, M Ehrhart, M Ravazzola, P Rosa, PH O'Farell, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, RV Floyd, S Bonner-Weir, S Lenzen, UK Laemmli, UM Benedum, WB Huttner, WJ Smith, WN Burnette   +44 more
core   +1 more source

Chromogranin A in the olfactory system of the rat [PDF]

, 1990
The olfactory bulb of the rat contains chromogranin A at a similar level as the adrenal gland or the hypophysis as revealed by immunoblots. Olfactory chromogranin A also displays the same size as chromogranin A of endocrine cells.
Baker, Bulenda, Bööj, Doolittle, Efendic, Ehrlich, Fasciotto, Forss-Petter, Gerdes, Gorr, Halász, Helle, Iacangelo, Kaplan, Kawakubo, Ley, Lizardi, Nolan, O'Connor, O'Connor, O'Connor, Parmer, Reiffen, Reiffen, Ruppert, Schilling, Schmid, Simon, Simon, Somogyi, Sternberger, Switzer, Volknandt   +32 more
core   +1 more source

Serum catestatin level in preeclampsia [PDF]

Scripta Medica
Background/Aim: Preeclampsia, a significant cause of maternal morbidity and mortality, is linked to increased cardiovascular risks. Catestatin regulates cardiovascular function which indicates its usefulness in understanding pathophysiology of ...
Alghazali Basima Sh, Tabarak Karim Mahdi
doaj   +1 more source

Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]

, 1988
We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M., Gratzl, Manfred, Grube, D., Jörns, A.   +3 more
core   +1 more source