Results 11 to 20 of about 2,220 (203)
Human Meningiomas Reveal No Evidence of Neuroendocrine Differentiation. [PDF]
ABSTRACT Meningiomas are heterogeneous tumors and studies suggest that meningiomas might be part of MEN1 syndrome. The tumors express somatostatin receptors (SSTRs) comparable to that seen in neuroendocrine neoplasms. We aimed to explore neuroendocrine differentiation in meningiomas by investigating the following neuroendocrine markers: neural cell ...
Tollefsen SE +7 more
europepmc +2 more sources
The role of chromogranins in the secretory pathway
Chromogranins (Cgs) are acidic proteins implicated in several physiological processes, including the biogenesis and sorting of secretory vesicles, the generation of bioactive peptides, and the accumulation of soluble species inside large dense core ...
Estevez-Herrera Judith +5 more
doaj +1 more source
Chromogranin A in neurons of the rat cerebellum and spinal cord: quantification and sites of expression [PDF]
Chromogranin A (CGA) is an abundant protein of dense-cored secretory vesicles in endocrine and neuronal cells. The present study, for the first time, compares CGA of neurons of the central nervous system with the CGA of adrenal origin.
Bergmann, M. +4 more
core +1 more source
Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer +50 more
core +1 more source
An unusual case of proton pump inhibitor induced hyperchromograninemia
Objective: To describe an unusual case of symptomatic hyperchromograninemia associated with proton pump inhibitor (PPI) use. Case Summary: A 55-year-old man with stage 1 follicular lymphoma and GERD on omeprazole presented with symptoms suggesting ...
Kwabena Oware Adu-Gyamfi +2 more
doaj +1 more source
Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga364–384) [PDF]
In the heart, the secretory granules containing the atrial natriuretic peptides (ANP) and B-type myocardial natriuretic peptide (BNP) provide the basis for the endocrine function of this organ.
Nilima Biswas +3 more
core +2 more sources
Ca2+ binding to Chromaffin Vesicle Matrix Proteins [PDF]
Recently we found that Ca2+ within chromaffin vesicles is largely bound [Bulenda, D., & Gratzl, M. (1985) Biochemistry 24, 7760-77651. In order to explore the nature of these bonds, we analyzed the binding of Ca2+ to the vesicle matrix proteins as well ...
Gratzl, Manfred, Reiffen, F. U.
core +1 more source
Objectives: Chromogranins (Cg) and secretogranins (Sg) are expressed by endocrine cells and may be important for the pathophysiology of ulcerative colitis (UC).
Maria K. Magnusson +5 more
doaj +1 more source
Matrix-free calcium in isolated chromaffin vesicles [PDF]
Isolated secretory vesicles from bovine adrenal medulla contain 80 nmol of Ca2+ and 25 nmol of Mg2+ per milligram of protein. As determined with a Ca2+-selective electrode, a further accumulation of about 160 nmol of Ca2+/mg of protein can be attained ...
Bashford L. C. +35 more
core +2 more sources
Chromogranin A and chromogranin B in pancreatic neuroendocrine tumors
For the first time in Russia a comparative study of chromogranin A (CgA) and chromogranin B (CgB) in neuroendocrine tumors (NETs) of the pancreas was performed. We examined 50 primary patients with pancreatic NETs and 42 healthy people. The determination of CgA and CgB was performed in blood serum using standard enzyme-linked immunoassay test-systems ...
N. V. Lyubimova +3 more
openaire +2 more sources

