Results 91 to 100 of about 12,444 (248)

Chromone Indole‐Pyrazole Cobalt Nanoparticle‐Based Electrochemical Immunosensor for Insulin Antibody Detection

ChemNanoMat, Volume 11, Issue 12, December 2025.
A highly sensitive electrochemical immunosensor is developed using chromone indole‐pyrazole cobalt nanoparticles on a platinum electrode for the detection of insulin antibodies. The immunosensor shows excellent selectivity, low detection limit (0.34 ng mL−1), and strong recovery in serum, enabling precise monitoring of type 1 diabetes biomarkers.
Senzekile Majola, Robert Gengan, Talent Makhanya, Myalowenkosi Sabela   +3 more
wiley   +1 more source

Natural chromones targeting autophagy signalling pathways as potential anticancer interventions: a systematic review

Results in Chemistry
Chromones, a class of natural product-based compounds, have garnered considerable interest due to their potential anticancer properties, particularly through the modulation of autophagy. Autophagy is a cellular process involved in both cancer progression
Nur Farisya Shamsudin, Amira Rusyda Mat Nawi, Ibrahim Jantan, Emil Salim, Maryam Aisyah Abdullah, Suet Lin Chia, Norazalina Saad, Syahrul Imran, Sze-Wei Leong, Firzan Nainu, Hafid Syahputra, Suryati Syafri, Kamal Rullah   +12 more
doaj   +1 more source

A comparison of the structures of some 2- and 3-substituted chromone derivatives: a structural study on the importance of the secondary carboxamide backbone for the inhibitory activity of MAO-B

Acta Crystallographica Section E: Crystallographic Communications, 2015
The crystal structures of the 3-substituted tertiary chromone carboxamide derivative, C17H13NO3, N-methyl-4-oxo-N-phenyl-4H-chromene-3-carboxamide (1), and the chromone carbonyl pyrrolidine derivatives, C14H13NO3, 3-(pyrrolidine-1-carbonyl)-4H-chromen-4 ...
Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Alexandra Gaspar, Fernanda Borges   +4 more
doaj   +1 more source

Facile Transfer Hydrogenation of Chromones.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Subir Kumar Sabui, Pranab Mondal, Ramanathapuram V. Venkateswaran   +2 more
openaire   +1 more source

Rumex Species: Phytochemistry, Pharmacology and Nutritional Potential for Food and Health Applications

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
Rumex dentatus, R. vesicarius, and Emex spinosa are traditionally used for managing gastrointestinal, respiratory, hepatic, and inflammatory disorders. In addition to their ethnomedicinal value, some species are consumed as wild edibles. Pharmacological studies support their antimicrobial, antioxidant, hepatoprotective, cytotoxic, and antidiabetic ...
Mai Mohamed Gohar, Shahira Mohamed Ezzat, Balakyz Yeskaliyeva, Seham Salaheldin Elhawary, Farid Noshey Kirollos, Aya Khouchlaa, Abdelhakim Bouyahya, Daniela Calina, Javad Sharifi‐Rad, William N. Setzer, Miquel Martorell   +10 more
wiley   +1 more source

2-(4-Arylbuta-1,3-dien- or 1-en-3-yn-1-yl)chromones as synthons for the synthesis of other nitrogen and oxygen heterocyclic compounds [PDF]

, 2014
It is well known the great biological relevance of oxygen and nitrogen heterocycles. Herein, the reactivity of 2-(4-aryl-1,3-dien- and 1-en-3-yn-1-yl)chromones are explored in order to establish new synthetic routes towards the preparation of new ...
Albuquerque, Hélio, Cavaleiro, José, Santos, Clementina M.M., Silva, Artur   +3 more
core  

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context [PDF]

, 2012
The aryl hydrocarbon receptor (AhR) mediates the induction of a variety of xenobiotic metabolism genes. Activation of the AhR occurs through binding to a group of structurally diverse compounds, most notably dioxins, which are exogenous ligands ...
BALBONI, GIANFRANCO, Bell DR, CONGIU, CENZO, Denison MS, Fernandes A, He G, Mellor I.R., ONNIS, VALENTINA, Rose M, Rowlands JC, Wall RJ   +10 more
core   +1 more source

5,6-Dihydro-2H-pyran-3(4H)-on als Baustein zur Synthese pyrananellierter Heterocyclen [PDF]

, 1984
Während 5,6-Dihydro-2H-pyran-3(4H)-on (3) sich mit ortho-substituierten Phenylcarbonylverbindungen nur in Einzelfällen regioselektiv zu pyrananellierten Heterocyclen umsetzt - z. B.
Eiden, Fritz, Wanner, Klaus Th.
core   +1 more source

Five 2-(2-Phenylethyl)chromones from Sodium Chloride-Elicited Aquilaria sinensis Cell Suspension Cultures

Molecules, 2016
Five 2-(2-phenylethyl)chromones including a new one, (5S,6R,7S,8R)-5,8-dichloro-6,7-dihydroxy-2-phenylethyl-5,6,7,8-tetrahydro-4H-chromen-4-one (1), and four known ones (2–5), were isolated from 150 mM NaCl-elicited Aquilaria sinensis cell suspension ...
Zhongxiu Zhang, Xiaohui Wang, Wanqing Yang, Juan Wang, Cong Su, Xiao Liu, Jun Li, Yunfang Zhao, Shepo Shi, Pengfei Tu   +9 more
doaj   +1 more source