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Chromophobe renal cell carcinoma with neuroendocrine differentiation

APMIS, 2008
Chromophobe renal cell carcinoma was described by Thoenes et al. in 1986, and associations with carcinoma of collecting ducts, conventional renal cell carcinoma and sarcomatoid renal cell carcinoma have been described. We report a case of chromophobe renal cell carcinoma which showed neuroendocrine differentiation.
David D, Parada, Karla B G, Peña
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Pathobiology and prognosis of chromophobe renal cell carcinoma

Urologic Oncology: Seminars and Original Investigations, 2008
To analyze pathobiology and prognosis of chromophobe renal cell carcinoma (CRCC).We studied 124 patients with CRCC who underwent nephrectomy from 1989 to 2006 at two institutions. Clinicopathological characteristics and survival were compared with 1,693 consecutive patients with clear-cell RCC.Compared with clear cell RCC, patients with CRCC presented ...
Tobias, Klatte   +7 more
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c-Met in chromophobe renal cell carcinoma

Medical Oncology, 2016
c-Met plays a role as a prognostic marker in clear cell renal cell carcinoma. In addition, recently the tyrosine kinase inhibitor cabozantinib targeting c-Met was approved for the treatment of advanced renal cell carcinoma (RCC). In contrast to clear cell RCC, little is known about c-Met expression patterns in rarer RCC subtypes.
Franziska, Erlmeier   +6 more
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Pigmented microcystic chromophobe renal cell carcinoma

Pathology - Research and Practice, 2007
We report a case of a 60-year-old female with a pigmented microcystic chromophobe renal cell carcinoma (PMCRCC). The tumor was 4.5 cm in diameter, and was located in the right kidney. Grossly, on cross section, the tumor was light gray with multiple small brown to black pigmented foci up to 0.2 cm in diameter.
Pavel, Dundr   +6 more
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Detection of renin in chromophobe renal cell carcinomas

Actas Urológicas Españolas (English Edition), 2010
To evaluate frequency of renin detection in chromophobe renal cell carcinoma, and if this expression was associated to systemic high blood pressure.A descriptive retrospective study. All the cases with confirmed diagnosis of chromophobe carcinoma and resected between 1990 and 2004 were included in our study: 31 cases from 31 patients ...
L F, Arias, P, Bruneval, J, Blanco
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Rhabdoid differentiation of chromophobe renal cell carcinoma

Pathology, 2003
Rhabdoid change represents an aggressive form of divergent differentiation previously reported in conventional (clear-cell) and papillary renal cell carcinoma. This study aims to characterise rhabdoid differentiation in a case of chromophobe renal cell carcinoma (ChRCC) and to investigate its origin by genetic analysis.A large tumour mass arising in ...
Beverley A, Shannon, Ronald J, Cohen
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SYNCHRONOUS BILATERAL CHROMOPHOBE CELL RENAL CARCINOMA

Journal of Urology, 2001
In 1985 Thoenes et al described a new entity designated chromophobe cell renal carcinoma. Chromophobe cell renal carcinoma represents less than 5% of all types of renal cell carcinoma.1 This tumor warrants distinction from other variants because of its unique morphology and cytogenetic features, and the possibility of misdiagnosing the tumor as an ...
H H, Yakout   +5 more
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Metastatic chromophobe renal cell carcinoma to the brain

Journal of Clinical Neuroscience, 2016
Metastases represent the most common tumors of the central nervous system, with clear cell renal cell carcinomas showing a particular predilection to involve the brain. This report documents an unusual case of a patient with a chromophobe renal cell carcinoma presenting with a brain metastasis.
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Chromophobe renal cell carcinoma with sarcomatoid transformation

Annals of Diagnostic Pathology, 2003
We present a rare case of a chromophobe renal cell carcinoma that progressed to a high-grade spindle cell sarcoma. The tumor affected a 50-year-old man who had presented with right upper quadrant discomfort and hematuria and subsequently underwent a right radical nephrectomy.
Neil A, Abrahams   +2 more
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Chromophobe Cell Renal Carcinoma: Clinicopathological Features of 50 Cases

Journal of Urology, 1995
We review the clinicopathological features of chromophobe cell renal carcinoma.Cases were identified by reviewing the histology of all renal neoplasms resected between 1977 and 1990. Clinical data were obtained by chart review.Of 50 cases a majority (53%) were discovered incidentally and most (86%) were stage I.
T B, Crotty, G M, Farrow, M M, Lieber
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