Results 161 to 170 of about 1,291,704 (346)
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu+10 more
wiley +1 more source
Determinants and clinical implications of chromosomal instability in cancer
Laurent Sansregret+2 more
semanticscholar +1 more source
DECENT is a deep learning method that enhances noninvasive preimplantation genetic testing by accurately reconstructing embryonic copy number variations (CNVs) from cell‐free DNA in spent embryo culture media. By mitigating maternal contamination, DECENT improves diagnostic accuracy, even with high contamination levels, offering a reliable, noninvasive
Zhenyi Zhang+3 more
wiley +1 more source
DISPROPORTIONATE SYNTHESIS OF DNA IN A POLYTENE CHROMOSOME REGION
George T. Rudkin, Sally L. Corlette
openalex +1 more source
The sex chromosome in the house mouse [PDF]
Ronald Aylmer Fisher+2 more
openalex +1 more source
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo+16 more
wiley +1 more source
Localisation of chromosome breakage at meiosis [PDF]
H. Rees, J B Thompson
openalex +1 more source