Results 221 to 230 of about 1,291,704 (346)

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

The Analysis of Chromosome Pairing in <i>Triticum</i> Hybrids

, 1931
C. D. Darlington
openalex   +2 more sources

Chromosomal Inversions and Their Potential Impact on the Evolution of Arboviral Vector Aedes aegypti. [PDF]

Genome Biol Evol
Liang J, Rose NH, Brusentsov II, Lukyanchikova V, Karagodin DA, Feng Y, Yurchenko AA, Sharma A, Sylla M, Lutomiah J, Badolo A, Aribodor O, Gonzalez Acosta C, Alto BW, Ahmad NW, Baricheva EM, Tu Z, Ayala D, Gloria-Soria A, Black WC, Powell JR, Sharakhov IV, McBride CS, Sharakhova MV.   +23 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

The Effect of Temperature on Linkage in the Second Chromosome of Drosophila

, 1917
H. H. Plough
openalex   +1 more source

Discovery of new chromosomal markers through repeatome analysis of Caryophyllaeus laticeps (Caryophyllidea). [PDF]

Parasitol Res
Marková A, Orosová M.
europepmc   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

The hidden causes of pregnancy loss: a closer look. [PDF]

J Transl Med
Shi P, Wang C, Liang H, Zhu X, Wang X, Ning Y, Leigh D, Cram DS, Kong X.   +8 more
europepmc   +1 more source

Chromosomal passengers [PDF]

Current Biology, 2001
openaire   +2 more sources

Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity

Cell, 2007
W. Shen, A. Balajee, Jianli Wang, Hong Wu, C. Eng, P. Pandolfi, Yuxin Yin   +6 more
semanticscholar   +1 more source