Epidemiological Surveillance of Genetically Determined Microcephaly in Latin America: A Narrative Review. [PDF]
Gonzalez-Fernandez MD+8 more
europepmc +1 more source
A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia+14 more
wiley +1 more source
Genetic Evidence of Aberrant Chromosome Behavior in Maize Endosperm
R. A. Emerson
openalex +2 more sources
Modeling the t(2;5) Translocation of Anaplastic Large Cell Lymphoma Using CRISPR-Mediated Chromosomal Engineering. [PDF]
Khan R+16 more
europepmc +1 more source
Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang+13 more
wiley +1 more source
CCRR: a user-friendly platform for analyzing complex chromosomal rearrangements in tumors. [PDF]
Liu J+9 more
europepmc +1 more source
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu+5 more
wiley +1 more source
Paternal UPD (15) With Disease-Causing Mutation and Small Supernumerary Ring Chromosome 15: A Case Report. [PDF]
Lee Curtis D+4 more
europepmc +1 more source
The NLR protein PibH8 interacts with phenylalanine ammonia‐lyase OsPAL1 and E3 ubiquitin ligase OsFBK16. Through competitive binding, PibH8 weakens the interaction between OsFBK16 and OsPAL1, thereby reducing the degradation of OsPAL1 by OsFBK16. The Hap1 allele of PibH8 exhibits a higher expression level than Hap2, thus accumulating more PibH8 protein,
Denghao Xiang+17 more
wiley +1 more source
Distinct chromosome abnormality patterns for differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma. [PDF]
Ngamsangiam W+8 more
europepmc +1 more source