Results 291 to 300 of about 1,274,518 (371)
The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan+13 more
wiley +1 more source
Epigenetic state and gene expression remain stable after CRISPR/Cas-mediated chromosomal inversions. [PDF]
Khosravi S+5 more
europepmc +1 more source
Cytological Studies on Rumes L. I. Chromosomes of Rumes Acetosa L
Hitoshi Kihara, Tomowo Ono
openalex +2 more sources
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang+13 more
wiley +1 more source
ChromInst: a multicentre evaluation of robustness in aneuploidy and structural rearrangement testing. [PDF]
Niu W+21 more
europepmc +1 more source
This study investigates bidirectional introgression between Chinese and European pig populations, revealing 3558 introgressed genomic segments and 30 structural variations. Analysis of the BMP2 region suggests its role in body size enhancement. By integrating ancient and modern genomes, the study highlights the impact of introgression on genetic ...
Yibin Qiu+19 more
wiley +1 more source
How should antenatal counseling be given to parents in the fetal corpus callosum agenesis? [PDF]
Süt H, Yıldız GA.
europepmc +1 more source
The study reports that Wnt inhibitors safeguard porcine embryonic stem cells (ESCs) from acquiring the extraembryonic endoderm (XEN) lineage, and further develop an efficient strategy to derive XEN cells from ESCs. The XEN cells from ESCs exhibit similar transcriptome and chromatin accessibility features to XEN cells from embryos and contribute to ...
Hanning Wang+4 more
wiley +1 more source
The Heterogeneity of 13q Deletions in Chronic Lymphocytic Leukemia: Diagnostic Challenges and Clinical Implications. [PDF]
Xia C+9 more
europepmc +1 more source