Results 31 to 40 of about 1,728,680 (388)
CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations
Nature Communications, 2019 CRISPR-Cas9 is a promising technology for genome editing. Here we use Cas9 nuclease-induced double-strand break DNA (DSB) at the UROS locus to model and correct congenital erythropoietic porphyria.
G. Cullot +19 more
semanticscholar +1 more source
Chromoanagenesis: cataclysms behind complex chromosomal rearrangements
Molecular Cytogenetics, 2019 Background During the last decade, genome sequencing projects in cancer genomes as well as in patients with congenital diseases and healthy individuals have led to the identification of new types of massive chromosomal rearrangements arising during ...
Franck Pellestor
doaj +1 more source
BMC Pregnancy and Childbirth, 2021 Background In the entire population, an aberrant right subclavian artery (ARSA) is closely associated with chromosomal abnormalities. ARSA with additional ultrasonic findings would increase risk of chromosomal abnormalities. The risk of fetal chromosomal
Li-Ping Chen +8 more
doaj +1 more source
Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries [PDF]
, 1992 We established chromosomal homologies between all chromosomes of the human karyotype and that of an old world monkey (Macaca fuscata) by chromosomal in situ suppression (CISS) hybridization with human chromosome specific DNA libraries.
Cremer, Thomas +3 more
core +1 more source
Seminars in Cell & Developmental Biology, 2021 Our understanding of the structure and function of mitotic chromosomes has come a long way since these iconic objects were first recognized more than 140 years ago, though many details remain to be elucidated. In this chapter, we start with the early history of chromosome studies and then describe the path that led to our current understanding of the ...
James R. Paulson +3 more
openaire +2 more sources
Reactions of Triticum urartu accessions to two races of the wheat yellow rust pathogen
Crop Journal, 2018 Triticum urartu (AA, 2n = 2x = 14), a wild grass endemic to the Fertile Crescent (FC), is the progenitor of the A subgenome in common wheat. It belongs to the primary gene pool for wheat improvement. Here, we evaluated the yellow rust (caused by Puccinia
Jibin Xiao +9 more
doaj +1 more source
Antenatal screening for chromosomal and genetic abnormalities:Cost effectiveness and outcome [PDF]
Journal of Analytical Research in Clinical Medicine, 2018 Introduction: As an essential part of antenatal care, pregnant women of all ages should be offered screening for chromosomal abnormalities before 20 weeks of gestation.
Simin Tagavi +7 more
doaj +1 more source
Chromosomal control of pig populations in France: 2002-2006 survey [PDF]
, 2007 The chromosomal control of pig populations has been widely developed in France over the last ten years. By December 31st, 2006, 13 765 individuals had been karyotyped in our laboratory, 62% of these since 2002.
Berland, Hélène-Marie +8 more
core +4 more sources
Organization of Chromosomal DNA by SMC Complexes.
Annual Review of Genetics, 2019 Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and ...
S. Yatskevich, James Rhodes, K. Nasmyth
semanticscholar +1 more source
Cells, 2019 Induced pluripotent stem cells (iPSCs) have revolutionized the study of human diseases as they can renew indefinitely, undergo multi-lineage differentiation, and generate disease-specific models. However, the difficulty of working with iPSCs is that they
Nejla Erkilic +14 more
doaj +1 more source