Results 31 to 40 of about 1,274,518 (371)
Journal of Human Reproductive Sciences, 2021 Background: Recurrent pregnancy loss (RPL) is a common occurrence that affects up to 15% of couples in their reproductive years. In both males and females with RPL and infertility, chromosomal abnormalities play a significant impact.
Abhik Chakraborty +3 more
doaj +1 more source
Frontiers in Genetics, 2023 Purpose: To study the accuracy of non-invasive chromosomal screening (NICS) results, in normal chromosomes and chromosomal rearrangement groups and to investigate whether using trophoblast cell biopsy along with NICS, to choose embryos for transfer can ...
Bo-lan Sun +11 more
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Formation of Chromosomal Domains in Interphase by Loop Extrusion
bioRxiv, 2015 Topologically Associating Domains (TADs) are fundamental structural and functional building blocks of human interphase chromosomes, yet mechanisms of TAD formation remain unknown. Here we propose that loop extrusion underlies TAD formation.
G. Fudenberg +5 more
semanticscholar +1 more source
Cytogenetic findings in patients with intellectual disability and/or multiple congenital anomalies [PDF]
Journal of Analytical Research in Clinical Medicine, 2016 Introduction: Chromosomal abnormalities are a major etiology of intellectual disability (ID) and multiple congenital anomalies (MCAs). Screening for chromosomal aberrations by clinical diagnostic techniques has been primarily performed ...
Sima Derakhshan, Mahmoud Khaniani
doaj +1 more source
Shanghai yufang yixue, 2023 ObjectiveTo investigate the current status and high-risk factors of chromosomal aberrations in peripheral blood lymphocytes （PBL） of radiation workers in Hainan Province.MethodsA total of 200 radiological workers who underwent occupational health ...
ZHANG Yuhong +5 more
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Chromosome Structure: Coiling up chromosomes [PDF]
Current Biology, 1995 The mechanism by which eukaryotic chromosomes condense as cells enter mitosis has long been inaccessible to molecular biologists. An important clue has now been provided by a ubiquitous protein family, the SMCs.
openaire +3 more sources
BMC Microbiology, 2010 Background The chromosome of Streptomyces has been shown to be unstable, frequently undergoing gross chromosomal rearrangements. However, the mechanisms underlying this phenomenon remain unclear, with previous studies focused on two chromosomal ends as ...
Wen Ying +5 more
doaj +1 more source
ChrSNet: Chromosome Straightening using Self-attention Guided Networks [PDF]
arXiv, 2022 Karyotyping is an important procedure to assess the possible existence of chromosomal abnormalities. However, because of the non-rigid nature, chromosomes are usually heavily curved in microscopic images and such deformed shapes hinder the chromosome analysis for cytogeneticists.
arxiv
Organization of Chromosomal DNA by SMC Complexes.
Annual Review of Genetics, 2019 Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and ...
S. Yatskevich, James Rhodes, K. Nasmyth
semanticscholar +1 more source
A Mechanism Linking Extra Centrosomes to Chromosomal Instability
Nature, 2009 Chromosomal instability (CIN) is a hallmark of many tumours and correlates with the presence of extra centrosomes. However, a direct mechanistic link between extra centrosomes and CIN has not been established.
Neil J. Ganem, S. Godinho, D. Pellman
semanticscholar +1 more source