Results 251 to 260 of about 859,918 (327)
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On the formation of chromosomal aberrations
Mutation Research, 1970Abstract The exchange hypothesis and the breakage-first hypothesis are the 2 major hypotheses that describe how chromosomal aberrations might be produced. A critical test has shown that one important aspect of the exchange hypothesis is correct, namely that some aberrations that appear to be simple chromatid deletions are actually incomplete ...
J A, Heddle, D J, Bodycote
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The fate of chromosome aberrations
Journal of Theoretical Biology, 1973Abstract Chromosomal aberrations rapidly disappear from populations of dividing cells, but little is known about the details of the process. One may ask, for example, whether a cell with an acentric fragment is virtually certain to die after the first mitosis or whether it has a high probability of surviving to the second.
A V, Carrano, J A, Heddle
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Chromosomal numerical aberration pattern in papillary renal cell carcinoma: Review article.
Annals of Diagnostic Pathology, 2017Traditionally, papillary renal cell carcinomas (PRCCs) have been divided in two subgroups - type 1 and type 2. Based on recent molecular and genetic developments in the understanding of RCCs, it seems that this traditional classification may not be ...
T. Pitra +3 more
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Advances in Space Research, 2001 Several advances have been achieved in the knowledge of nuclear architecture and functions during the last decade, thus allowing the identification of interphase chromosome territories and sub-chromosomal domains (e.g. arm and band domains).
A. Ottolenghi, F. Ballarini, M. Biaggi
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Chromosome Aberrations and Cancer
Science, 1991Cancer may be defined as a progressive series of genetic events that occur in a single clone of cells because of alterations in a limited number of specific genes: the oncogenes and tumor suppressor genes. The association of consistent chromosome aberrations with particular types of cancer has led to the identification of some of these genes and the ...
E, Solomon, J, Borrow, A D, Goddard
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Chromosomal aberrations in man
The Journal of Pediatrics, 1961Summary The following are the most significant points to emerge in summarizing the present status of the field of human cytogenetics. 1. The human chromosome number is 46; a standard system of nomenclature has been established for identification of somatic metaphase chromosomes.
S, RAPPOPORT, W D, KAPLAN
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ULTRASOUND AND CHROMOSOME ABERRATIONS
Medical Journal of Australia, 1973Human and marsupial whole blood and blood-medium mixtures were irradiated with various doses of 2.25 MHz ultrasound and gamma rays. Doses of ultrasonic irradiation orders of magnitude higher than those used for diagnostic studies produced very few chromosome aberrations.
R D, Brock +4 more
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Heterochromatin and chromosome aberrations
Chromosoma, 1969The chromosome breaking effect of mitomycin C, methyl methanesulfonate, maleic hydrazide, 8-ethoxycaffeine and gamma rays on the primary root meristematic cells of Nigella damascena was studied. All the agents tested except 8-ethoxycaffeine, produced relatively fewer aberrations, when compared to Vicia faba cells, though both the species have nearly ...
A T, Natarajan, G, Ahnström
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Interpreting Chromosome Aberration Spectra
Journal of Computational Biology, 2007Ionizing radiation can damage cells by breaking both strands of DNA in multiple locations, essentially cutting chromosomes into pieces. The cell has enzymatic mechanisms to repair such breaks; however, these mechanisms are imperfect and, in an exchange process, may produce a large-scale rearrangement of the genome, called a chromosome aberration ...
Dan Levy +6 more
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Chromosomal aberrations in malnutrition
Metabolism, 1975The effects of feeding high (18%) and low (5%) protein diets on chromosomal aberrations in bone marrow cells of rats were investigated. Malnourished rats maintained on low protein diet had significantly higher incidence of breaks and deletions as compared to wellfed rats maintained on high protein diet. Well fed rats showed an increased aberration rate
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