Results 101 to 110 of about 33,239 (264)
Loss of E3 ligase HvST1 function substantially increases distal crossover frequency. [PDF]
New PhytolSummary This study characterizes the function of a grass‐specific E3 ubiquitin ligase, HvST1, in regulating synapsis and crossover (CO) formation during meiosis in barley (Hordeum vulgare). In large‐genome cereals, COs are predominantly restricted to distal chromosomal regions, limiting genetic recombination and breeding flexibility.
Orr JN +8 more
europepmc +2 more sources
XSim: Simulation of Descendants from Ancestors with Sequence Data. [PDF]
, 2015 Real or imputed high-density SNP genotypes are routinely used for genomic prediction and genome-wide association studies. Many researchers are moving toward the use of actual or imputed next-generation sequence data in whole-genome analyses.
Cheng, Hao +2 more
core +2 more sources
Coarsening model of chromosomal crossover placement
11 pages, 6 figures, 24 pages of supporting ...
Ernst, Marcel +2 more
openaire +2 more sources
Structural Concrete, EarlyView.Abstract Fly ash foam composite concrete (FFC) is a sustainable, lightweight alternative to traditional concrete. However, accurately predicting its compressive strength (CS) through conventional laboratory methods is challenging due to its non‐linear behavior induced by the addition of foam content and fly ash. Also, the laboratory determination of CS
Atta Ullah +5 more
wiley +1 more source
Frontiers in Microbiology, 2017 Essential gene functions remain largely underexplored in bacteria. Clostridium cellulolyticum is a promising candidate for consolidated bioprocessing; however, its genetic manipulation to reduce the formation of less-valuable acetate is technically ...
Tao Xu +6 more
doaj +1 more source
Csm4-dependent telomere movement on nuclear envelope promotes meiotic recombination. [PDF]
PLoS Genetics, 2008 During meiotic prophase, chromosomes display rapid movement, and their telomeres attach to the nuclear envelope and cluster to form a "chromosomal bouquet." Little is known about the roles of the chromosome movement and telomere clustering in this phase.
Hiromichi Kosaka +2 more
doaj +1 more source
sequenceLDhot: Detecting Recombination Hotspots. [PDF]
, 2006 Motivation: There is much local variation in recombination rates across the human genome—with the majority of recombination occuring in recombination hotspots—short regions of around ~2 kb in length that have much higher recombination rates than ...
Fearnhead, Paul
core +1 more source
Multi‐Objective Optimisation Framework for Heterogeneous Federated Learning
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT Federated learning is a distributed framework that trains a centralised model using data from multiple clients without transferring that data to a central server. Despite rapid progress, federated learning still faces several unsolved challenges. Specifically, communication costs and system heterogeneity, such as nonidentical data distribution,
Jamshid Tursunboev +4 more
wiley +1 more source
eLife, 2013 During gamete formation, crossover recombination must occur on replicated DNA to ensure proper chromosome segregation in the first meiotic division. We identified a Mec1/ATR- and Dbf4-dependent replication checkpoint in budding yeast that prevents the ...
Hannah G Blitzblau, Andreas Hochwagen
doaj +1 more source
Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis. [PDF]
PLoS Genetics, 2013 Reduction in ploidy to generate haploid gametes during sexual reproduction is accomplished by the specialized cell division program of meiosis. Pairing between homologous chromosomes and assembly of the synaptonemal complex at their interface (synapsis ...
Susanna Mlynarczyk-Evans +2 more
doaj +1 more source