Results 131 to 140 of about 855,599 (268)

Targeted Deletion of the Cytopathogenic Toxin A Gene in Sneathia vaginalis

Molecular Microbiology, EarlyView.
Sneathia vaginalis is emerging as an important marker for preterm birth. Through this study, we developed a method for site‐directed mutagenesis in this species. The gene encoding the cytopathogenic toxin A (CptA) was deleted as a proof of principle, and the deletion mutant revealed that CptA is indispensable for the cytotoxic and hemolytic activities ...
Rishi M. Ray, Phoebe V. Bridy, Aubree G. Musicant, Shiny Chandravel, Youstina Y. Aziz, Jasmine C. Cruz, Kimberly K. Jefferson   +6 more
wiley   +1 more source

Analysis of the impact of the absence of RAD51 strand exchange activity in Arabidopsis meiosis.

PLoS ONE, 2017
The ploidy of eukaryote gametes must be halved to avoid doubling of numbers of chromosomes with each generation and this is carried out by meiosis, a specialized cell division in which a single chromosomal replication phase is followed by two successive ...
Gunjita Singh, Olivier Da Ines, Maria Eugenia Gallego, Charles I White   +3 more
doaj   +1 more source

Population‐wide single‐pollen nuclei genotyping in rye sheds light on the genetic basis and environmental plasticity of meiotic recombination

New Phytologist, EarlyView.
Summary The core molecular machinery of meiosis is conserved deep across eukaryotic lineages. Nevertheless, recombination landscapes vary at multiple scales, from chromosomes to populations, caused by an interaction between genetic and environmental factors.
Christina Waesch, Noah Gaede, Yixuan Gao, Matilda Ehle, Axel Himmelbach, Joerg Fuchs, Susan E. Johnston, Steven Dreissig   +7 more
wiley   +1 more source

Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica

New Phytologist, EarlyView.
Summary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Robin Burns, Anna Glushkevich, Aboli Kulkarni, Uliana K. Kolesnikova, Filip Kolář, Alison Dawn Scott, Polina Yu. Novikova   +6 more
wiley   +1 more source

A rapid and simple method for constructing stable mutants of Acinetobacter baumannii

BMC Microbiology, 2010
Background Acinetobacter baumannii is a multidrug-resistant bacterium responsible for nosocomial infections in hospitals worldwide. Study of mutant phenotypes is fundamental for understanding gene function.
Rodríguez-Velo Patricia, Parreira José R, Rumbo Carlos, Rumbo Soraya, Pardo Belén G, Poza Margarita, Aranda Jesús, Bou Germán   +7 more
doaj   +1 more source

Genetics by genetic algorithm: Defining an ideal platelet donor population to support patients with HLA‐mediated alloimmune refractoriness

Transfusion, EarlyView.
Abstract Background Immune factors underlie approximately 20% of patients exhibiting platelet transfusion refractoriness (PTR). PTR can be mitigated by supplying HLA‐A and B compatible platelets to these patients. Since 2019, Canadian Blood Services has managed a program to provide compatible platelets to alloimmunized patients.
J. T. Blake, N. Rickards, J. Mack, M. Seftel, A. Gupta   +4 more
wiley   +1 more source

Crossover-active regions of the wheat genome are distinguished by DMC1, the chromosome axis, H3K27me3, and signatures of adaptation [PDF]

, 2021
Andrew J. Tock, Daniel M. Holland, Wei Jiang, Kim Osman, Eugenio Sánchez‐Morán, James D. Higgins, Keith J. Edwards, Cristóbal Uauy, F. Chris H. Franklin, Ian R. Henderson   +9 more
openalex   +1 more source

Spectral Analysis of Guanine and Cytosine Fluctuations of Mouse Genomic DNA

, 2004
We study global fluctuations of the guanine and cytosine base content (GC%) in mouse genomic DNA using spectral analyses. Power spectra S(f) of GC% fluctuations in all nineteen autosomal and two sex chromosomes are observed to have the universal ...
Bernardi G., Calladine C. R., Clay O., Daniell P. J., DIRK HOLSTE, Gerton J. L., Kong A., Li W., Li W., Mansilla R., Meyer A., Press W., Priestley M. B., Waterston R. H., WENTIAN LI, West B. J.   +15 more
core   +1 more source

Development of a Model for Predicting the Thermophysical Properties of Carbon Materials and Proposal of Manufacturing Conditions Using the Model

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT A steelmaking method using electric furnaces is attracting attention in the iron and steel industry, and a carbon material called needle coke is used as an aggregate for the electrode in electric steelmaking. The performance of needle coke as an aggregate for electrodes in steelmaking is greatly affected by the quality of the needle coke ...
Masayoshi Matsubara, Ryo Sasaki, Jun P. Takahara, Shinji Moritake, Yasuyuki Harada, Hiromasa Kaneko   +5 more
wiley   +1 more source

Crossovers trigger a remodeling of meiotic chromosome axis composition that is linked to two-step loss of sister chromatid cohesion [PDF]

, 2008
Enrique Martínez-Pérez, Mara Schvarzstein, Consuelo Barroso, James W. Lightfoot, Abby F. Dernburg, Anne M. Villeneuve   +5 more
openalex   +1 more source