Results 161 to 170 of about 33,239 (264)

The asexual genome of Drosophila

open access: yes, 2017
The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic segments ...
Lässig, Michael   +2 more
core   +1 more source

Crossover recombination between homologous chromosomes in meiosis: recent progress and remaining mysteries

open access: yesTrends in Genetics
Crossing over between homologous chromosomes in meiosis is essential in most eukaryotes to produce gametes with the correct ploidy. Meiotic crossovers are typically evenly spaced, with each homolog pair receiving at least one crossover. The association of crossovers with distal sister chromatid cohesion is critical for the proper segregation of ...
Lisette Payero, Eric Alani
openaire   +2 more sources

Protocol for Constructing a Gene Knockout in Pseudomonas Using pT18mobsacB

open access: yesFood Safety and Health, Volume 4, Issue 1, Page 259-267, January 2026.
A streamlined protocol for scarless gene knockout in Pseudomonas using the tetracycline‐resistant suicide plasmid pT18mobsacB is presented. The method enables efficient two‐step allelic exchange and is broadly applicable to Gram‐negative bacteria. ABSTRACT Gene knockout via homologous recombination is a powerful approach for investigating gene function
Han Yang   +4 more
wiley   +1 more source

Prenatally Diagnosed 7q11.23 Copy Number Variations: A Retrospective Case Series

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
Prenatal 7q11.23 CNVs exhibit 100% ultrasound anomalies in deletions (cardiovascular defects, growth restriction) and 50% in duplications. Inherited CNVs (50% deletions, 43% duplications) correlate with milder outcomes, while de novo variants drive high TOP rates (76.5%), emphasizing genomic testing and parental studies for precise counseling. ABSTRACT
Jiong Yan, Ziyang Liu, Song Yi, Nian Liu
wiley   +1 more source

Functional synergy and genomic linkage of glyphosate resistance traits in Canada fleabane

open access: yesPest Management Science, Volume 82, Issue 1, Page 305-318, January 2026.
Stacking target‐site and non‐target‐site glyphosate resistance mechanisms in Conyza canadensis results in strong synergistic effects. This study quantifies gene × gene interactions and maps linked resistance loci, advancing our understanding of herbicide resistance genetics and informing management strategies.
Eric R Page   +4 more
wiley   +1 more source

Successful Live Birth Following PGT‐SR in a Couple Who Were Both Carriers of Balanced Reciprocal Translocations Identified During Recurrent Pregnancy Loss Workup: A Case Report

open access: yesReproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Case A non‐consanguineous couple with recurrent pregnancy loss was found to be carriers of two different balanced reciprocal translocations: 46,XX,t(13;16)(q14;q23) and 46,XY,t(4;12)(q21.1;q15). They underwent IVF with PGT‐SR, from which seven blastocysts were obtained.
Hiroaki Negishi   +8 more
wiley   +1 more source

Bipartite recruitment of PCH2 and COMET to the synaptonemal complex drives chromosome axis reconstruction leading to crossover restriction [PDF]

open access: gold, 2022
Chao Yang   +7 more
openalex   +1 more source

Heavy‐Haul Railway Alignment Design Considering the Heavy‐to‐Light Ratio and Regenerative Braking Energy

open access: yesIET Intelligent Transport Systems, Volume 20, Issue 1, January/December 2026.
This study proposes an NSGA‐II framework enhanced with struct‐based encoding for bi‐objective optimization of heavy‐haul railway vertical alignment (construction cost and energy consumption), which requires no preset vertical points of intersection (VPIs) and inherently meets most constraints.
Shengda Zhuo   +4 more
wiley   +1 more source

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